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LOC127828264 H3K27ac hESC enhancer GRCh37_chr14:91315826-91316592 [ Homo sapiens (human) ]

Gene ID: 127828264, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127828264
Gene description
H3K27ac hESC enhancer GRCh37_chr14:91315826-91316592
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127828264 in Genome Data Viewer
Location:
chromosome: 14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (90849482..90850248)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (85075067..85075833)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (91315826..91316592)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 7B Neighboring gene ReSE screen-validated silencer GRCh37_chr14:91260136-91260298 Neighboring gene ribosomal protein S18 pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6013 Neighboring gene MPRA-validated peak2229 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6014 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:91311907-91312408 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:91312409-91312908 Neighboring gene long intergenic non-protein coding RNA 2321 Neighboring gene ribosomal protein S6 kinase A5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8883 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8884 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8885 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8886 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8887 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8889 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8888 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6015 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6016 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:91526715-91527295 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6018 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8890 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8891 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:91579864-91580776 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:91582717-91583218 Neighboring gene D-glutamate cyclase Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:91585689-91586888 Neighboring gene RNA, U7 small nuclear 30 pseudogene Neighboring gene small nucleolar RNA, H/ACA box 11B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_129763.1 

    Range
    101..867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    90849482..90850248
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    85075067..85075833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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