U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127891253 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:34972391-34973046 [ Homo sapiens (human) ]

Gene ID: 127891253, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127891253
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:34972391-34973046
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC127891253 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (34481486..34482141)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (37026049..37026704)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (34972391..34973046)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904695 Neighboring gene programmed cell death 2 like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10502 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10503 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10504 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:34928566-34928723 Neighboring gene MPRA-validated peak3443 silencer Neighboring gene ubiquitin like modifier activating enzyme 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:34971736-34972390 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:34973047-34973701 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:34988289-34989176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:34989177-34990063 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10505 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:34994324-34995145 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:34996156-34996656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:34996657-34997157 Neighboring gene WT1 interacting protein Neighboring gene ribosomal protein S26 pseudogene 55 Neighboring gene uncharacterized LOC105372374 Neighboring gene zinc finger protein 807, pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_141131.1 

    Range
    101..756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    34481486..34482141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791809.1 Reference GRCh38.p14 PATCHES

    Range
    146506..147161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    37026049..37026704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases