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LOC127891708 NANOG-H3K27ac hESC enhancer GRCh37_chr19:45582765-45583532 [ Homo sapiens (human) ]

Gene ID: 127891708, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127891708
Gene description
NANOG-H3K27ac hESC enhancer GRCh37_chr19:45582765-45583532
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127891708 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (45079507..45080274)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (47904638..47905405)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45582765..45583532)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CLK4 associating serine/arginine rich protein Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45552602-45553156 Neighboring gene RNA, U6 small nuclear 611, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14778 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10750 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10751 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10752 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10753 Neighboring gene zinc finger protein 296 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45584301-45585066 Neighboring gene gem nuclear organelle associated protein 7 Neighboring gene GEMIN7 antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45593049-45594044 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45594045-45595039 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14780 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10754 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45600806-45601394 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45601395-45601984 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45603163-45603750 Neighboring gene protein phosphatase 1 regulatory subunit 37 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45608463-45609052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45619689-45620344 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14781 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14782 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14783 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14784 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14785 Neighboring gene eukaryotic translation initiation factor 5A pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_141563.1 

    Range
    101..868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    45079507..45080274
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    47904638..47905405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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