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LOC127894487 NANOG hESC enhancer GRCh37_chr21:28224660-28225227 [ Homo sapiens (human) ]

Gene ID: 127894487, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894487
Gene description
NANOG hESC enhancer GRCh37_chr21:28224660-28225227
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894487 in Genome Data Viewer
Location:
chromosome: 21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (26852341..26852908)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (25210761..25211328)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (28224660..28225227)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene CYYR1 antisense RNA 1 Neighboring gene uncharacterized LOC107985474 Neighboring gene cysteine and tyrosine rich 1 Neighboring gene NANOG hESC enhancer GRCh37_chr21:28191085-28191706 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:28214275-28215474 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:28217912-28218512 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:28218513-28219112 Neighboring gene uncharacterized LOC105372760 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 1 Neighboring gene NANOG hESC enhancer GRCh37_chr21:28282232-28282780 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_61884 Neighboring gene VISTA enhancer hs1684 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 5 Neighboring gene microRNA 4759

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_144143.1 

    Range
    101..668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    26852341..26852908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    25210761..25211328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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