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LOC127895513 H3K4me1 hESC enhancer GRCh37_chr22:23599428-23600084 [ Homo sapiens (human) ]

Gene ID: 127895513, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127895513
Gene description
H3K4me1 hESC enhancer GRCh37_chr22:23599428-23600084
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127895513 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (23257241..23257897)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (23680120..23680776)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23599428..23600084)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene radial spoke head 14 homolog Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:23491660-23492160 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:23492161-23492661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23498179-23498784 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23508841-23509342 Neighboring gene RAB36, member RAS oncogene family Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18748 Neighboring gene Sharpr-MPRA regulatory region 7478 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18749 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13533 Neighboring gene RAB36-BCR intergenic enhancer-blocking element 22-1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:23521616-23522426 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13534 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13535 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13536 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23526972-23527478 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23535027-23535526 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23534525-23535026 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23536731-23537231 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23541159-23542100 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:23543528-23543704 Neighboring gene BCR pseudogene 8 Neighboring gene BCR activator of RhoGEF and GTPase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:23559755-23560544 Neighboring gene BCR-ABL minor-breakpoint cluster region Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18750 Neighboring gene Sharpr-MPRA regulatory region 5876 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:23564024-23564225 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:23571548-23572282 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18751 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:23584482-23585232 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:23585233-23585984 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:23591289-23591814 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18753 Neighboring gene RNA, 7SL, cytoplasmic 263, pseudogene Neighboring gene F-box and WD repeat domain containing 4 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_148246.1 

    Range
    101..757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    23257241..23257897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    23680120..23680776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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