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LOC127896344 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41075515-41076208 [ Homo sapiens (human) ]

Gene ID: 127896344, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127896344
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41075515-41076208
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127896344 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (40679511..40680204)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (41151476..41152169)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (41075515..41076208)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905122 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr22:41047623-41048822 Neighboring gene CRISPRi-validated cis-regulatory element chr22.2152 Neighboring gene uncharacterized LOC124905123 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:41060823-41061338 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:41072002-41072502 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41076631-41077585 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41077586-41078539 Neighboring gene glyceraldehyde 3 phosphate dehydrogenase pseudogene 37 Neighboring gene Sharpr-MPRA regulatory regions 5578 and 9058 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41079701-41080396 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41080397-41081092 Neighboring gene melanin concentrating hormone receptor 1 Neighboring gene Sharpr-MPRA regulatory region 1401 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:41107927-41108443 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41109407-41110282 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41110283-41111157 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:41111979-41112145 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:41117878-41118491 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41124025-41124749 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:41124750-41125473 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:41127319-41127477 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13774 Neighboring gene solute carrier family 25 member 17 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:41178069-41178568 Neighboring gene RFK pseudogene 4 Neighboring gene jumping translocation breakpoint pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_145876.1 

    Range
    101..794
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    40679511..40680204
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    41151476..41152169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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