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LOC127896758 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46483852-46484461 [ Homo sapiens (human) ]

Gene ID: 127896758, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127896758
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46483852-46484461
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127896758 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (46087972..46088581)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (46572541..46573150)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene collagen alpha-1(III) chain-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13897 Neighboring gene PRR34 long non-coding RNA Neighboring gene PRR34 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19231 Neighboring gene long intergenic non-protein coding RNA 2939 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13898 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13899 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46467816-46468370 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46468371-46468923 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46480369-46480940 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr22:46481213-46482412 Neighboring gene uncharacterized LOC112268288 Neighboring gene MIRLET7B host gene Neighboring gene microRNA 3619 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46500537-46501051 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46506657-46507190 Neighboring gene microRNA let-7a-3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146269.1 

    Range
    101..710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    46087972..46088581
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    46572541..46573150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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