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LOC127897191 OCT4-NANOG hESC enhancer GRCh37_chrX:10579147-10580022 [ Homo sapiens (human) ]

Gene ID: 127897191, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127897191
Gene description
OCT4-NANOG hESC enhancer GRCh37_chrX:10579147-10580022
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127897191 in Genome Data Viewer
Location:
chromosome: X
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (10611107..10611982)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (10193633..10194508)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:10141885-10142861 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20656 Neighboring gene chloride voltage-gated channel 4 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:10416979-10418178 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:10476778-10477647 Neighboring gene midline 1 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:10539598-10539816 Neighboring gene MID1 promoter D Neighboring gene uncharacterized LOC124905245 Neighboring gene RNA, U6 small nuclear 800, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chrX:10602208-10603407 Neighboring gene Sharpr-MPRA regulatory region 5514 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20657 Neighboring gene uncharacterized LOC124905244 Neighboring gene HCCS divergent transcript Neighboring gene Sharpr-MPRA regulatory region 6238

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146676.1 

    Range
    101..976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    10611107..10611982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    10193633..10194508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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