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LOC127897774 H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:70798494-70799135 [ Homo sapiens (human) ]

Gene ID: 127897774, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127897774
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:70798494-70799135
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127897774 in Genome Data Viewer
Location:
chromosome: X
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (71578644..71579285)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (70011895..70012536)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chrX:70752005-70753204 Neighboring gene SOCS6 pseudogene 1 Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase Neighboring gene germ cell nuclear acidic peptidase Neighboring gene Sharpr-MPRA regulatory region 14051 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29745 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29747 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29748 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29749 Neighboring gene Sharpr-MPRA regulatory region 2992 Neighboring gene C-X-C motif chemokine receptor 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29750 Neighboring gene chromosome X open reading frame 49 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29751 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29752

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_147127.1 

    Range
    101..742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    71578644..71579285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    70011895..70012536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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