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LOC128966794 CapStarr-seq enhancers MGSCv37_chr7:25692211-25692364 and MGSCv37_chr7:25692403-25692604 [ Mus musculus (house mouse) ]

Gene ID: 128966794, updated on 8-Feb-2024

Summary

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Gene symbol
LOC128966794
Gene description
CapStarr-seq enhancers MGSCv37_chr7:25692211-25692364 and MGSCv37_chr7:25692403-25692604
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region includes two candidate cis-regulatory modules (CRMs) that were identified in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. The major subregion was validated as an active enhancer by luciferase reporter assays in P5424 T cells. Two overlapping subregions were also validated as enhancers by high-throughput CapStarr-seq reporter assays in P5424 T cells, where one subregion had strong activity and the other had weak activity. [provided by RefSeq, Mar 2023]
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Genomic context

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Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24606426..24607010)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:25669584-25669693 Neighboring gene ribosomal protein S19 Neighboring gene STARR-positive B cell enhancer ABC_E10428 Neighboring gene STARR-positive B cell enhancer ABC_E1723 Neighboring gene CD79A antigen (immunoglobulin-associated alpha) Neighboring gene Rho guanine nucleotide exchange factor 1 Neighboring gene ETS repressor factor like Neighboring gene predicted gene, 36809

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq. Vanhille L, et al. Nat Commun, 2015 Apr 15. PMID 25872643

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • CapStarr-seq enhancer MGSCv37_chr7:25692211-25692364
  • CapStarr-seq enhancer MGSCv37_chr7:25692403-25692604

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_153803.1 

    Range
    101..685
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    24606426..24607010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version