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LOC130056725 ATAC-STARR-seq lymphoblastoid active region 9166 [ Homo sapiens (human) ]

Gene ID: 130056725, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130056725
Gene description
ATAC-STARR-seq lymphoblastoid active region 9166
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130056725 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (29308295..29308374)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (27086668..27086747)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (29600499..29600578)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene DDB1 and CUL4 associated factor 6 pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:29561321-29561822 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:29561823-29562322 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:29611925-29612479 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:29637062-29638044 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:29699994-29700185 Neighboring gene MPRA-validated peak2283 silencer Neighboring gene Sharpr-MPRA regulatory region 8593 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr15:29903026-29903716 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr15:29903717-29904407 Neighboring gene Sharpr-MPRA regulatory region 3573 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29924029-29924548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29943839-29944339 Neighboring gene tubulin beta class I pseudogene 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29967552-29968082 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29968083-29968613 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:29970293-29970793 Neighboring gene lung cancer immune cell infiltration associated lncRNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_191146.1 

    Range
    101..180
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    29308295..29308374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    27086668..27086747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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