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Epn2 epsin 2 [ Mus musculus (house mouse) ]

Gene ID: 13855, updated on 9-Dec-2024

Summary

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Official Symbol
Epn2provided by MGI
Official Full Name
epsin 2provided by MGI
Primary source
MGI:MGI:1333766
See related
Ensembl:ENSMUSG00000001036 AllianceGenome:MGI:1333766
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ibp2; 9530051D10Rik
Summary
Predicted to enable clathrin binding activity and phospholipid binding activity. Acts upstream of or within Notch signaling pathway; embryonic organ development; and in utero embryonic development. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of clathrin coat of endocytic vesicle. Predicted to be active in endosome and plasma membrane. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human EPN2 (epsin 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in lung adult (RPKM 26.3), cerebellum adult (RPKM 19.7) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Epn2 in Genome Data Viewer
Location:
11 B2; 11 37.96 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (61406709..61470560, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (61515883..61579717, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6995 Neighboring gene mitogen-activated protein kinase 7 Neighboring gene B9 protein domain 1, opposite strand Neighboring gene B9 protein domain 1 Neighboring gene STARR-seq mESC enhancer starr_29682 Neighboring gene STARR-positive B cell enhancer ABC_E3957 Neighboring gene STARR-positive B cell enhancer ABC_E3958 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:61483303-61483412 Neighboring gene GRB2-related adaptor protein Neighboring gene solute carrier family 5 (sodium/glucose cotransporter), member 10 Neighboring gene family with sequence similarity 83, member G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte. Li L, et al. Oncotarget, 2016 Aug 9. PMID 27463009, Free PMC Article
  2. Motif mimetic of epsin perturbs tumor growth and metastasis. Dong Y, et al. J Clin Invest, 2015 Dec. PMID 26571402, Free PMC Article
  3. Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling. Dong Y, et al. Cells, 2021 Jul 29. PMID 34440686, Free PMC Article
  4. Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery. Kay BK, et al. Protein Sci, 1999 Feb. PMID 10048338, Free PMC Article
  5. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. Song K, et al. J Clin Invest, 2021 Jan 4. PMID 32960814, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.
    Title: Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.
  2. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
    Title: Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
  3. Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
    Title: Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
  4. Diabetes attenuated VEGF-C-induced lymphangiogenesis in corneal micropocket and Matrigel plug assays in WT mice but not in mice with inducible lymphatic-specific deficiency of epsins 1 and 2 (LEC-iDKO).
    Title: Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.
  5. our data identify Epsin2 as a novel player in regulating oocyte maturation, and demonstrate that Epsin2 promotes polarity establishment and meiotic division via activating Cdc42
    Title: Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte.
  6. Epsins are required for Dishevelled stability and Wnt signalling activation in colon cancer development.
    Title: Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.
  7. epsins 1 and 2 have a critical role in the temporal and spatial regulation of VEGFR3 abundance and signaling in collecting lymphatic trunks during lymphatic valve formation
    Title: Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
  8. Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.
    Title: Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.
  9. Epsins function specifically to downregulate VEGFR2 by mediating activated VEGFR2 internalization and degradation and that genetic reduction of VEGFR2 level protects against excessive angiogenesis caused by epsin loss.
    Title: Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
  10. Loss of epsins 1 and 2 impaired endocytosis and degradation of VEGFR2, resulting in excessive VEGF signaling and compromised tumor vascular function.
    Title: Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within embryonic organ development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within in utero embryonic development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of Notch signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of clathrin coat of endocytic vesicle ISO
Inferred from Sequence Orthology
more info
  
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epsin-2
Names
EPS-15-interacting protein 2
intersectin-EH-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252188.2 → NP_001239117.1  epsin-2 isoform 1

    See identical proteins and their annotated locations for NP_001239117.1

    Status: VALIDATED

    Source sequence(s)
    AK139234, AK160782, AL604029
    Consensus CDS
    CCDS56780.1
    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Related
    ENSMUSP00000136950.2, ENSMUST00000179936.8
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  2. NM_001252189.2 → NP_001239118.1  epsin-2 isoform 3

    See identical proteins and their annotated locations for NP_001239118.1

    Status: VALIDATED

    Source sequence(s)
    AK160782, AL604029
    Consensus CDS
    CCDS56779.1
    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Related
    ENSMUSP00000104353.2, ENSMUST00000108713.8
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  3. NM_001362585.1 → NP_001349514.1  epsin-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL604029
    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  4. NM_001362586.1 → NP_001349515.1  epsin-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL604029
    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  5. NM_001362587.1 → NP_001349516.1  epsin-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL604029
    Consensus CDS
    CCDS24816.1
    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  6. NM_010148.4 → NP_034278.1  epsin-2 isoform 2

    See identical proteins and their annotated locations for NP_034278.1

    Status: VALIDATED

    Source sequence(s)
    AK160782, AL604029, CX123717
    Consensus CDS
    CCDS24816.1
    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Related
    ENSMUSP00000001063.9, ENSMUST00000001063.15
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    61406709..61470560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532165.5 → XP_006532228.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532228.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  2. XM_036156313.1 → XP_036012206.1  epsin-2 isoform X6

  3. XM_036156312.1 → XP_036012205.1  epsin-2 isoform X5

  4. XM_030245537.2 → XP_030101397.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  5. XM_030245533.2 → XP_030101393.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Related
    ENSMUSP00000136553.2, ENSMUST00000178202.8
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  6. XM_006532171.5 → XP_006532234.1  epsin-2 isoform X2

    See identical proteins and their annotated locations for XP_006532234.1

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Related
    ENSMUSP00000104352.2, ENSMUST00000108712.8
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  7. XM_030245539.2 → XP_030101399.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  8. XM_036156302.1 → XP_036012195.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  9. XM_030245538.2 → XP_030101398.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  10. XM_006532166.5 → XP_006532229.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532229.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  11. XM_006532168.5 → XP_006532231.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532231.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  12. XM_036156307.1 → XP_036012200.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  13. XM_030245531.2 → XP_030101391.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  14. XM_030245528.2 → XP_030101388.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  15. XM_011248711.4 → XP_011247013.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_011247013.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  16. XM_036156305.1 → XP_036012198.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  17. XM_036156303.1 → XP_036012196.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  18. XM_006532167.5 → XP_006532230.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532230.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  19. XM_036156308.1 → XP_036012201.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  20. XM_036156296.1 → XP_036012189.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  21. XM_036156292.1 → XP_036012185.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  22. XM_036156306.1 → XP_036012199.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  23. XM_036156299.1 → XP_036012192.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  24. XM_036156291.1 → XP_036012184.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  25. XM_036156309.1 → XP_036012202.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Related
    ENSMUSP00000104351.2, ENSMUST00000108711.8
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  26. XM_030245534.2 → XP_030101394.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  27. XM_036156301.1 → XP_036012194.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  28. XM_006532170.5 → XP_006532233.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532233.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  29. XM_036156297.1 → XP_036012190.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  30. XM_036156311.1 → XP_036012204.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  31. XM_036156300.1 → XP_036012193.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  32. XM_036156295.1 → XP_036012188.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  33. XM_036156310.1 → XP_036012203.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  34. XM_036156293.1 → XP_036012186.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  35. XM_030245540.2 → XP_030101400.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  36. XM_030245535.2 → XP_030101395.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  37. XM_006532169.5 → XP_006532232.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_006532232.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  38. XM_036156294.1 → XP_036012187.1  epsin-2 isoform X1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  39. XM_036156304.1 → XP_036012197.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  40. XM_030245530.2 → XP_030101390.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    J3QNT7, Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  41. XM_011248713.4 → XP_011247015.1  epsin-2 isoform X1

    See identical proteins and their annotated locations for XP_011247015.1

    UniProtKB/TrEMBL
    Q5NCM5
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  42. XM_030245541.2 → XP_030101401.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  43. XM_030245532.2 → XP_030101392.1  epsin-2 isoform X3

    UniProtKB/Swiss-Prot
    O70447, Q5NCM4, Q8BZ85, Q8CHU3
    UniProtKB/TrEMBL
    Q5NCM6
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

  44. XM_030245536.1 → XP_030101396.1  epsin-2 isoform X4

    UniProtKB/TrEMBL
    Q5NCM6, Q5NCM7
    Conserved Domains (1) summary
    cd16990
    Location:19 → 141
    ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CHU3.1 GenPept UniProtKB/Swiss-Prot:Q8CHU3

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