Zfp358 zinc finger protein 358 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp358provided by MGI
Official Full Name: zinc finger protein 358provided by MGI
Primary source: MGI:MGI:2153740
See related: Ensembl:ENSMUSG00000047264 AllianceGenome:MGI:2153740
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Zfend
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including eye; genitourinary system; integumental system; limb; and nervous system. Orthologous to human ZNF358 (zinc finger protein 358). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in ovary adult (RPKM 53.8), whole brain E14.5 (RPKM 46.6) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 A1.1; 8 1.92 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (3543138..3547208)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (3493138..3497208)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 358

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_080461.2 → NP_536709.2 zinc finger protein 358

Status: VALIDATED

Source sequence(s)

AC170806, BY007922, BY749799

Consensus CDS

CCDS40205.1

UniProtKB/TrEMBL

E9Q8M1, Q6PI88

Related

ENSMUSP00000060344.8, ENSMUST00000061508.8

Conserved Domains (4) summary

sd00017
Location:268 → 288

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:154 → 176

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:169 → 193

zf-H2C2_2; Zinc-finger double domain

pfam15909
Location:295 → 373

zf-C2H2_8; C2H2-type zinc ribbon