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E1 E1 [ Iotapapillomavirus 1 ]

Gene ID: 1489000, updated on 15-Aug-2018

Summary

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Gene symbol
E1
Gene description
E1
Locus tag
MrpVgp3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Iotapapillomavirus 1 (nat-host: Mastomys natalensis)
Lineage
Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Iotapapillomavirus
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Genomic context

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Sequence:
NC_001605.1 (787..2595)

NC_001605.1Genomic Context describing neighboring genes Neighboring gene E6 protein Neighboring gene E7 protein Neighboring gene E2 protein Neighboring gene L2 protein Neighboring gene major capsid L1 protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001605.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Mastomys natalensis papillomavirus: nucleotide sequence, genome organization, and phylogenetic relationship of a rodent papillomavirus involved in tumorigenesis of cutaneous epithelia. Tan CH, et al. Virology, 1994 Feb. PMID 8291235

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
E1
NP_042016.1
  • E1; The Papillomaviriuses are icosahedral dsDNA viruses that encode 7 early proteins, E1 to E7, and 2 late structural proteins L1 and L2. Host infection by members of the papillomaviruses gives rise to warts and cancer in some instances. The E1 helicase protein is an ATP-dependent DNA helicase that facilitates the inititiation of viral DNA replication through its interactions with the viral E2 protein. The E1-E2 complex binds to the viral origin of replication where E1 acts to unwind the DNA and E2 acts as a transcriptional activator.

VOG classification

Description:

  • VOGd0421 [L] * Replication protein E1 (helicase)
  • DNA Replication, Repair and Nucleotide Metabolism

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001605.1 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_042016.1 E1 protein [Iotapapillomavirus 1]

    See identical proteins and their annotated locations for NP_042016.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q84356
    Conserved Domains (3) summary
    PHA02774
    Location:1 → 602
    PHA02774; E1; Provisional
    pfam00519
    Location:162 → 593
    PPV_E1_C; Papillomavirus helicase
    pfam00524
    Location:6 → 116
    PPV_E1_N; E1 Protein, N terminal domain
Nucleotide Protein
Heading Accession and Version

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