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INp32 [ Avian leukosis virus - RSA ]

Gene ID: 1491901, updated on 9-Sep-2020

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Summary

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Gene symbol: INp32
Locus tag: ALVgp09
Gene type: other
Organism: Avian leukosis virus - RSA
Lineage: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus
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Genomic context

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Sequence:: NC_001408.1 (4211..5179)

NC_001408.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_001408.1

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Bibliography

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Related articles in PubMed

Ubiquitination of non-lysine residues in the retroviral integrase. Wang Z, et al. Biochem Biophys Res Commun, 2017 Dec 9. PMID 29054407
Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase. Charmetant J, et al. Virology, 2011 Dec 5. PMID 21982594

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 integrase has previously been reported to be regulated by ubiquitination, but the molecular characterization of integrase ubiquitination is still unclear. In this study, we analyzed the ubiquitination of avian leukosis virus (ALV) integrase in detail. The ubiquitination assay showed that, like HIV-1, ALV integrase could also be modified by ubiquitination when expressed in 293 T and DF-1 cells.
Title: Ubiquitination of non-lysine residues in the retroviral integrase.
The central core domain of integrase is required to form dimers and tetramers but is not essential for virus integration.
Title: Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase.

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General gene information

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Miscellaneous features

Loc: 4211-5179 integrase

protein_bind

Loc: 4747-4758 bound_moiety = nucleocapsid

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INp32 [Avian leukosis virus - RSA]
INp32 [Avian leukosis virus - RSA]
Gene ID:1491901

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