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env envelope protein [ Avian leukosis virus - RSA ]

Gene ID: 1491907, updated on 31-Jan-2024

Summary

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Gene symbol
env
Gene description
envelope protein
Locus tag
ALVgp01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Avian leukosis virus - RSA
Lineage
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus
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Genomic context

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Sequence:
NC_001408.1 (372..6872)

NC_001408.1Genomic Context describing neighboring genes Neighboring gene trans-acting factor Neighboring gene Neighboring gene Neighboring gene Neighboring gene Neighboring gene Neighboring gene polymerase Neighboring gene Neighboring gene Neighboring gene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001408.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Bipartite Sequence Motif in the N and C Termini of gp85 of Subgroup J Avian Leukosis Virus Plays a Crucial Role in Receptor Binding and Viral Entry. Zhang Y, et al. J Virol, 2020 Oct 27. PMID 32878894, Free PMC Article
  2. Identification of a novel B-cell epitope specific for avian leukosis virus subgroup J gp85 protein. Li X, et al. Arch Virol, 2015 Apr. PMID 25655260
  3. Inhibition of avian leukosis virus subgroup J replication by miRNA targeted against env. Wang W, et al. Virus Genes, 2013 Aug. PMID 23546824, Free PMC Article
  4. [Effect of YXXM motif on viral replication of subgroup J avian leukosis virus]. Feng S, et al. Wei Sheng Wu Xue Bao, 2011 Dec. PMID 22379808
  5. Studies of the "chain reversal regions" of the avian sarcoma/leukosis virus (ASLV) and ebolavirus fusion proteins: analogous residues are important, and a His residue unique to EnvA affects the pH dependence of ASLV entry. Delos SE, et al. J Virol, 2010 Jun. PMID 20335266, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Bipartite Sequence Motif in the N and C Termini of gp85 of Subgroup J Avian Leukosis Virus Plays a Crucial Role in Receptor Binding and Viral Entry.
    Title: The Bipartite Sequence Motif in the N and C Termini of gp85 of Subgroup J Avian Leukosis Virus Plays a Crucial Role in Receptor Binding and Viral Entry.
  2. (134)AEAELRDFI(142) was the minimal linear epitope for avian leukosis virus subgroup J gp85 protein.
    Title: Identification of a novel B-cell epitope specific for avian leukosis virus subgroup J gp85 protein.
  3. Downregulation of the env expression by miRNA inhibited the virus replication.
    Title: Inhibition of avian leukosis virus subgroup J replication by miRNA targeted against env.
  4. THe YXXM motif of env was important for virus replication in DF-1 cells.
    Title: [Effect of YXXM motif on viral replication of subgroup J avian leukosis virus].
  5. a His residue that is unique to the chain reversal region of ASLV EnvA controls the pH at which ASLV entry occurs.
    Title: Studies of the "chain reversal regions" of the avian sarcoma/leukosis virus (ASLV) and ebolavirus fusion proteins: analogous residues are important, and a His residue unique to EnvA affects the pH dependence of ASLV entry.
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General gene information

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Homology

Miscellaneous features

  • Loc: 1836-2102 nucleocapsid protein
  • Loc: 2103-2474 neutral protease large subunit
  • Loc: 2495-4210 reverse transcriptase alpha-subunit
  • Loc: 2495-5179 reverse transcriptase beta-subunit
  • Loc: 372-2474 3' imperfect repeat; matrix protein
  • Loc: 4211-5179 integrase
  • Loc: 512-540 dimer linkage structure
  • Loc: 5244-6260 surface protein
  • Loc: 536-556 dimer linkage structure
  • Loc: 6261-6869 transmembrane protein
  • Loc: 701-792 negative splicing regulator
  • Loc: 817-876 enhancer domain

General protein information

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Preferred Names
envelope protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001408.1 Reference assembly

    Range
    372..6872
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_040548.1 envelope protein [Avian leukosis virus - RSA]

    See identical proteins and their annotated locations for NP_040548.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03397, P0DTM4, Q03803, Q85500
    UniProtKB/TrEMBL
    Q90VD6, Q90VD7
    Conserved Domains (2) summary
    cd09949
    Location:447 → 518
    RSV-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region (ectodomain) of the transmembrane subunit of Rous sarcoma virus (RSV), and related domains
    pfam03708
    Location:157 → 402
    Avian_gp85; Avian retrovirus envelope protein, gp85
Nucleotide Protein
Heading Accession and Version

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