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HRV89gp1 genome polyprotein [ Rhinovirus A ]

Gene ID: 1493933, updated on 18-Jul-2024

Summary

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Gene symbol
HRV89gp1
Gene description
genome polyprotein
Locus tag
HRV89gp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rhinovirus A (serotype: 89)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Ensavirinae; Enterovirus
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Genomic context

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Sequence:
NC_001617.1 (619..7113)

NC_001617.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001617.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups.
    Title: RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups.
  2. The overall shape of the substrate is important in determining binding specificity of human rhinovirus 2Apro.
    Title: Specificity of human rhinovirus 2A(pro) is determined by combined spatial properties of four cleavage site residues.
  3. LVLQTM peptide acted as a pseudosubstrate of the viral 2A cysteine protease and inhibited its activity and virus replication.
    Title: Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease.
  4. These data show that in HRV-1A infection, the 3A protein plays a role in fragmenting the Golgi complex and generating vesicles that are used as the site of viral RNA replication.
    Title: Fragmentation of the Golgi apparatus provides replication membranes for human rhinovirus 1A.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
genome polyprotein
Names
capsid protein VP4
capsid protein VP2
capsid protein VP3
capsid protein VP1
P2-A polypeptide
P2-B polypeptide
P2-C polypeptide
P-3A polypeptide
VPg polypeptide
protease 3C
RNA-directed RNA polymerase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001617.1 Reference assembly

    Range
    619..7113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_042288.1 genome polyprotein [Rhinovirus A]

    See identical proteins and their annotated locations for NP_042288.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P07210, Q82096, Q82097, Q82098, Q82099, Q82100, Q82101, Q82102, Q82103, Q82104, Q82105
    UniProtKB/TrEMBL
    B9V4A5

  2. NP_740391.1 capsid protein VP4

    UniProtKB/TrEMBL
    A0MHA8, E3W0Z2, Q80SH8, Q80SK1, Q80SM3, Q80SQ7

  3. NP_740392.1 capsid protein VP2

  4. NP_740393.1 capsid protein VP3

  5. NP_740394.1 capsid protein VP1

    UniProtKB/TrEMBL
    Q7T5X5

  6. NP_740395.1 P2-A polypeptide

  7. NP_740396.1 P2-B polypeptide

  8. NP_740397.1 P2-C polypeptide

  9. NP_740398.1 P-3A polypeptide

  10. NP_740399.1 VPg polypeptide

  11. NP_740400.1 protease 3C

  12. NP_740401.1 RNA-directed RNA polymerase

Protein Accession Links
GenPept Link UniProtKB Link
CAA00931.1

Gene LinkOut

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