Kif1b kinesin family member 1B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Kif1bprovided by MGI
Official Full Name: kinesin family member 1Bprovided by MGI
Primary source: MGI:MGI:108426
See related: Ensembl:ENSMUSG00000063077 AllianceGenome:MGI:108426
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D4Mil1e; KIF1Bp130; KIF1Bp204; A530096N05Rik
Summary: Enables plus-end-directed microtubule motor activity. Involved in chemical synaptic transmission and organelle transport along microtubule. Located in mitochondrion. Is active in postsynapse and synaptic vesicle membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and skeletal musculature. Used to study Charcot-Marie-Tooth disease type 2A1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; hepatocellular carcinoma; multiple sclerosis; neuroblastoma; and ovary epithelial cancer. Orthologous to human KIF1B (kinesin family member 1B). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in cerebellum adult (RPKM 37.2), cortex adult (RPKM 32.4) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 E2; 4 79.05 cM

Exon count:: 51

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (149260776..149392762, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (149176319..149307773, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These data have supported the relevance of KIF1Bbeta in IGF1R transport, which may give new clue to the neuropathic pathogenesis.
Title: KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth.
study demonstrates that mouse KIF1B is important for spindle assembly, chromosome congression, and mitochondrial distribution during oocyte maturation and early embryonic development.
Title: Loss of function of KIF1B impairs oocyte meiotic maturation and early embryonic development in mice.
pathogenic KIF1Bbeta mutations identified in neuroblastoma impair TRKA transport.
Title: Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.
activity-dependent synaptic recruitment of KIF1Bbeta, its interaction with Ca(2 ) sensor Calmodulin and its role as a dendritic motor of ribonucleoprotein complexes provide a novel basis for understanding the coordination of motor protein mobilization and synaptic signaling pathways
Title: KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner.
KIF1Bbeta maps to chromosome 1p36.2, which is frequently deleted in neural crest-derived tumors including neuroblastomas.
Title: The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Kif1Bbeta isoform is enriched in motor neurons but is unchanged in a mouse model of amyotrophic lateral sclerosis
Title: Kif1Bbeta isoform is enriched in motor neurons but does not change in a mouse model of amyotrophic lateral sclerosis.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Gene trapped (1)
Targeted (5) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AB023656 (e-PCR)
- UniSTS:185605

BB168181 (e-PCR)
- UniSTS:185606

NoName (e-PCR)
- UniSTS:235097

D4Mit49 (e-PCR), detects polymorphism
- UniSTS:130167

AI506502 (e-PCR)
- UniSTS:164268

AI448212 (e-PCR)
- UniSTS:164270

RH137798 (e-PCR)
- UniSTS:219885

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	ISO Inferred from Sequence Orthology more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables kinase binding	ISO Inferred from Sequence Orthology more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	TAS Traceable Author Statement more info	PubMed
enables microtubule motor activity	IEA Inferred from Electronic Annotation more info
enables microtubule motor activity	ISO Inferred from Sequence Orthology more info
enables plus-end-directed microtubule motor activity	IBA Inferred from Biological aspect of Ancestor more info
enables plus-end-directed microtubule motor activity	IDA Inferred from Direct Assay more info	PubMed
enables plus-end-directed microtubule motor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables plus-end-directed microtubule motor activity	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables scaffold protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in anterograde neuronal dense core vesicle transport	ISO Inferred from Sequence Orthology more info
involved_in anterograde synaptic vesicle transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in apoptotic process involved in development	ISO Inferred from Sequence Orthology more info
involved_in embryo development ending in birth or egg hatching	NAS Non-traceable Author Statement more info	PubMed
involved_in lysosome localization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mitochondrion transport along microtubule	IDA Inferred from Direct Assay more info	PubMed
involved_in mitochondrion transport along microtubule	IDA Inferred from Direct Assay more info	PubMed
involved_in mitochondrion transport along microtubule	ISO Inferred from Sequence Orthology more info
involved_in neuromuscular synaptic transmission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron-neuron synaptic transmission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in protein localization to cell periphery	ISO Inferred from Sequence Orthology more info
involved_in retrograde neuronal dense core vesicle transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde neuronal dense core vesicle transport	ISO Inferred from Sequence Orthology more info
involved_in transport along microtubule	ISO Inferred from Sequence Orthology more info
involved_in vesicle transport along microtubule	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in axon cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasmic vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic vesicle	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic vesicle	ISS Inferred from Sequence or Structural Similarity more info
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
part_of kinesin complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
is_active_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed
located_in neuron projection	ISO Inferred from Sequence Orthology more info
located_in neuron projection	ISS Inferred from Sequence or Structural Similarity more info
is_active_in postsynapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in presynapse	IDA Inferred from Direct Assay more info	PubMed
NOT located_in synaptic membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in synaptic vesicle membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: kinesin-like protein KIF1B

Names: N-3 kinesin; kinesin heavy chain member 1B

NP_001277924.1

EC 5.6.1.3

NP_032467.2

EC 5.6.1.3

NP_997565.2

EC 5.6.1.3

XP_006538653.1

EC 5.6.1.3

XP_006538654.1

EC 5.6.1.3

XP_006538655.1

EC 5.6.1.3

XP_006538656.1

EC 5.6.1.3

XP_006538657.1

EC 5.6.1.3

XP_006538658.1

EC 5.6.1.3

XP_006538659.1

EC 5.6.1.3

XP_011248502.1

EC 5.6.1.3

XP_030109128.1

EC 5.6.1.3

XP_030109129.1

EC 5.6.1.3

XP_030109130.1

EC 5.6.1.3

XP_030109131.1

EC 5.6.1.3

XP_030109132.1

EC 5.6.1.3

XP_030109133.1

EC 5.6.1.3

XP_036019636.1

EC 5.6.1.3

XP_036019637.1

EC 5.6.1.3

XP_036019638.1

EC 5.6.1.3

XP_036019639.1

EC 5.6.1.3

XP_036019640.1

EC 5.6.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001290995.1 → NP_001277924.1 kinesin-like protein KIF1B isoform c

See identical proteins and their annotated locations for NP_001277924.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c).

Source sequence(s)

AF131865, AI848477, AK134946, BC059901, BE952257, CF746574, CJ104954

Consensus CDS

CCDS71521.1

UniProtKB/Swiss-Prot

Q60575, Q9R0B4, Q9WVE5, Q9Z119

UniProtKB/TrEMBL

A0A5F8MPF0

Related

ENSMUSP00000056754.7, ENSMUST00000060537.13

Conserved Domains (9) summary

smart00129
Location:5 → 361

KISc; Kinesin motor, catalytic domain. ATPase

cd00060
Location:532 → 636

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1701 → 1799

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam00169
Location:1702 → 1795

PH; PH domain

pfam12423
Location:845 → 892

KIF1B; Kinesin protein 1B

pfam12473
Location:1313 → 1413

DUF3694; Kinesin protein

pfam16183
Location:358 → 555

Kinesin_assoc; Kinesin-associated

cl09111
Location:662 → 717

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
NM_008441.2 → NP_032467.2 kinesin-like protein KIF1B isoform a

See identical proteins and their annotated locations for NP_032467.2

Status: VALIDATED

Description

Transcript Variant: This variant (1) contains multiple coding region differences, including an alternate 3' terminal exon, compared to variant 3. It encodes isoform a, which is shorter and has a distinct C-terminus, compared to isoform c.

Source sequence(s)

AK134946, AL731655, CJ130277, D17577

Consensus CDS

CCDS18957.1

UniProtKB/TrEMBL

A2AH75

Related

ENSMUSP00000030806.6, ENSMUST00000030806.6

Conserved Domains (4) summary

smart00129
Location:5 → 355

KISc; Kinesin motor, catalytic domain. ATPase

cd00060
Location:486 → 590

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:352 → 509

Kinesin_assoc; Kinesin-associated
NM_207682.2 → NP_997565.2 kinesin-like protein KIF1B isoform b

See identical proteins and their annotated locations for NP_997565.2

Status: VALIDATED

Description

Transcript Variant: This variant (2) contains multiple coding region differences, compared to variant 3. The resulting isoform (b) is shorter than isoform c.

Source sequence(s)

AK041278, AK134946, AK147409, BC059901, CJ130277

Consensus CDS

CCDS18956.1

UniProtKB/TrEMBL

A0A5F8MPF0

Related

ENSMUSP00000061472.9, ENSMUST00000055647.15

Conserved Domains (9) summary

smart00129
Location:5 → 355

KISc; Kinesin motor, catalytic domain. ATPase

cd00060
Location:486 → 590

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1655 → 1753

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam00169
Location:1656 → 1749

PH; PH domain

pfam12423
Location:799 → 846

KIF1B; Kinesin protein 1B

pfam12473
Location:1267 → 1367

DUF3694; Kinesin protein

pfam16183
Location:352 → 509

Kinesin_assoc; Kinesin-associated

cl09111
Location:616 → 671

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000070.7 Reference GRCm39 C57BL/6J

Range

149260776..149392762 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030253270.2 → XP_030109130.1 kinesin-like protein KIF1B isoform X12

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:486 → 590

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1572 → 1670

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:799 → 845

KIF1B; Kinesin protein 1B

pfam12473
Location:1137 → 1284

DUF3694; Kinesin protein

pfam16183
Location:352 → 509

Kinesin_assoc; Kinesin-associated

cl09111
Location:616 → 671

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_036163744.1 → XP_036019637.1 kinesin-like protein KIF1B isoform X9

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (6) summary

cd00060
Location:512 → 616

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1598 → 1696

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:825 → 871

KIF1B; Kinesin protein 1B

pfam12473
Location:1163 → 1310

DUF3694; Kinesin protein

pfam16183
Location:352 → 535

Kinesin_assoc; Kinesin-associated
XM_030253268.2 → XP_030109128.1 kinesin-like protein KIF1B isoform X3

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:512 → 616

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1681 → 1779

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:825 → 872

KIF1B; Kinesin protein 1B

pfam12473
Location:1246 → 1393

DUF3694; Kinesin protein

pfam16183
Location:352 → 535

Kinesin_assoc; Kinesin-associated

cl09111
Location:642 → 697

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_036163743.1 → XP_036019636.1 kinesin-like protein KIF1B isoform X8

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (6) summary

cd00060
Location:526 → 630

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1612 → 1710

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:839 → 885

KIF1B; Kinesin protein 1B

pfam12473
Location:1177 → 1324

DUF3694; Kinesin protein

pfam16183
Location:352 → 549

Kinesin_assoc; Kinesin-associated
XM_036163745.1 → XP_036019638.1 kinesin-like protein KIF1B isoform X10

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (6) summary

cd00060
Location:500 → 604

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1586 → 1684

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:813 → 859

KIF1B; Kinesin protein 1B

pfam12473
Location:1151 → 1298

DUF3694; Kinesin protein

pfam16183
Location:352 → 523

Kinesin_assoc; Kinesin-associated
XM_030253269.1 → XP_030109129.1 kinesin-like protein KIF1B isoform X5

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:500 → 604

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1669 → 1767

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:813 → 860

KIF1B; Kinesin protein 1B

pfam12473
Location:1234 → 1381

DUF3694; Kinesin protein

pfam16183
Location:352 → 523

Kinesin_assoc; Kinesin-associated

cl09111
Location:630 → 685

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538590.4 → XP_006538653.1 kinesin-like protein KIF1B isoform X1

See identical proteins and their annotated locations for XP_006538653.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:526 → 630

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1695 → 1793

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:839 → 886

KIF1B; Kinesin protein 1B

pfam12473
Location:1260 → 1407

DUF3694; Kinesin protein

pfam16183
Location:352 → 549

Kinesin_assoc; Kinesin-associated

cl09111
Location:656 → 711

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538595.3 → XP_006538658.1 kinesin-like protein KIF1B isoform X11

See identical proteins and their annotated locations for XP_006538658.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:492 → 596

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1578 → 1676

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:805 → 851

KIF1B; Kinesin protein 1B

pfam12473
Location:1143 → 1290

DUF3694; Kinesin protein

pfam16183
Location:358 → 515

Kinesin_assoc; Kinesin-associated

cl09111
Location:622 → 677

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538593.3 → XP_006538656.1 kinesin-like protein KIF1B isoform X6

See identical proteins and their annotated locations for XP_006538656.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:492 → 596

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1661 → 1759

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:805 → 852

KIF1B; Kinesin protein 1B

pfam12473
Location:1226 → 1373

DUF3694; Kinesin protein

pfam16183
Location:358 → 515

Kinesin_assoc; Kinesin-associated

cl09111
Location:622 → 677

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538591.3 → XP_006538654.1 kinesin-like protein KIF1B isoform X2

See identical proteins and their annotated locations for XP_006538654.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:518 → 622

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1687 → 1785

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:831 → 878

KIF1B; Kinesin protein 1B

pfam12473
Location:1252 → 1399

DUF3694; Kinesin protein

pfam16183
Location:358 → 541

Kinesin_assoc; Kinesin-associated

cl09111
Location:648 → 703

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538592.3 → XP_006538655.1 kinesin-like protein KIF1B isoform X4

See identical proteins and their annotated locations for XP_006538655.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:506 → 610

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1675 → 1773

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:819 → 866

KIF1B; Kinesin protein 1B

pfam12473
Location:1240 → 1387

DUF3694; Kinesin protein

pfam16183
Location:358 → 529

Kinesin_assoc; Kinesin-associated

cl09111
Location:636 → 691

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538594.3 → XP_006538657.1 kinesin-like protein KIF1B isoform X7

See identical proteins and their annotated locations for XP_006538657.1

UniProtKB/TrEMBL

A0A5F8MPF0

Conserved Domains (7) summary

cd00060
Location:532 → 636

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01233
Location:1618 → 1716

PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:845 → 891

KIF1B; Kinesin protein 1B

pfam12473
Location:1183 → 1330

DUF3694; Kinesin protein

pfam16183
Location:358 → 555

Kinesin_assoc; Kinesin-associated

cl09111
Location:662 → 717

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_011250200.4 → XP_011248502.1 kinesin-like protein KIF1B isoform X13

See identical proteins and their annotated locations for XP_011248502.1

Conserved Domains (5) summary

cd00060
Location:532 → 636

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam12423
Location:845 → 892

KIF1B; Kinesin protein 1B

pfam16183
Location:358 → 555

Kinesin_assoc; Kinesin-associated

cl09111
Location:662 → 717

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
XM_006538596.3 → XP_006538659.1 kinesin-like protein KIF1B isoform X14

See identical proteins and their annotated locations for XP_006538659.1

Conserved Domains (3) summary

cd00060
Location:532 → 636

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:358 → 555

Kinesin_assoc; Kinesin-associated
XM_030253273.2 → XP_030109133.1 kinesin-like protein KIF1B isoform X19

Conserved Domains (3) summary

cd00060
Location:492 → 596

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:358 → 515

Kinesin_assoc; Kinesin-associated
XM_030253271.2 → XP_030109131.1 kinesin-like protein KIF1B isoform X16

Conserved Domains (3) summary

cd00060
Location:518 → 622

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 361

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:358 → 541

Kinesin_assoc; Kinesin-associated
XM_036163746.1 → XP_036019639.1 kinesin-like protein KIF1B isoform X15

Conserved Domains (3) summary

cd00060
Location:526 → 630

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:352 → 549

Kinesin_assoc; Kinesin-associated
XM_030253272.2 → XP_030109132.1 kinesin-like protein KIF1B isoform X17

Conserved Domains (3) summary

cd00060
Location:512 → 616

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:352 → 535

Kinesin_assoc; Kinesin-associated
XM_036163747.1 → XP_036019640.1 kinesin-like protein KIF1B isoform X18

Conserved Domains (3) summary

cd00060
Location:500 → 604

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd01365
Location:4 → 355

KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins

pfam16183
Location:352 → 523

Kinesin_assoc; Kinesin-associated