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ddx19b DEAD-box helicase 19b [ Danio rerio (zebrafish) ]

Gene ID: 192339, updated on 9-Dec-2024

Summary

Official Symbol
ddx19bprovided by ZNC
Official Full Name
DEAD-box helicase 19bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020419-30
See related
Ensembl:ENSDARG00000005699 AllianceGenome:ZFIN:ZDB-GENE-020419-30
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ddx19; fi21a04; chunp6915; wu:fb24g07; wu:fc59e08; wu:fd14f03; wu:fi21a04
Summary
Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be active in cytoplasmic stress granule and nucleus. Orthologous to several human genes including DDX19A (DEAD-box helicase 19A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ddx19b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (3524737..3535500, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (3505350..3516113, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b Neighboring gene pseudouridine synthase like 1 Neighboring gene si:dkey-33m11.7 Neighboring gene calcium/calmodulin dependent protein kinase II inhibitor 1 Neighboring gene si:dkey-33m11.8

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in poly(A)+ mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ATP-dependent RNA helicase DDX19B
Names
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
DEAD/H box polypeptide 19
NP_775365.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173258.1NP_775365.1  ATP-dependent RNA helicase DDX19B

    See identical proteins and their annotated locations for NP_775365.1

    Status: PROVISIONAL

    Source sequence(s)
    AY099536
    UniProtKB/TrEMBL
    Q7ZU28, Q8JGR1
    Related
    ENSDARP00000003250.4, ENSDART00000009788.7
    Conserved Domains (3) summary
    PTZ00424
    Location:99477
    PTZ00424; helicase 45; Provisional
    cd00079
    Location:315450
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cl21455
    Location:102304
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    3524737..3535500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)