EMX2OS EMX2 opposite strand/antisense RNA [Homo sapiens (human)] - Gene

Summary

Official Symbol: EMX2OSprovided by HGNC
Official Full Name: EMX2 opposite strand/antisense RNAprovided by HGNC
Primary source: HGNC:HGNC:18511
See related: Ensembl:ENSG00000229847 MIM:607637; AllianceGenome:HGNC:18511
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: EMX2-AS1; NCRNA00045
Expression: Biased expression in endometrium (RPKM 16.5), kidney (RPKM 12.5) and 5 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 10q26.11

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	10	NC_000010.11 (117484293..117545068, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	10	NC_060934.1 (118378722..118439451, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	10	NC_000010.10 (119243804..119304579, complement)

Chromosome 10 - NC_000010.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

EMX2OS targeting IGF2BP1 represses Wilms' tumour stemness,epithelial-mesenchymal transition and metastasis.
Title: EMX2OS targeting IGF2BP1 represses Wilms' tumour stemness,epithelial-mesenchymal transition and metastasis.
EMX2OS Delays Wilms'Tumor Progression via Targeting miR-654-3p.
Title: EMX2OS Delays Wilms'Tumor Progression via Targeting miR-654-3p.
EMX2OS plays a prognosis-associated enhancer RNA role in gastric cancer.
Title: EMX2OS plays a prognosis-associated enhancer RNA role in gastric cancer.
In the three variants of papillary thyroid cancer (PTC), EMX2 was significantly downregulated in classical PTC, while EMX2OS was significantly downregulated in follicular and classical PTC, compared with adjacent normal tissues. Kaplan-Meier survival curves showed that EMX2 and EMX2OS expression was not related to relapse-free survival in follicular PTC.
Title: The downregulation of lncRNA EMX2OS might independently predict shorter recurrence-free survival of classical papillary thyroid cancer.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

RH11265 (e-PCR)
- UniSTS:46092

D8S2279 (e-PCR)
- UniSTS:473907

G35510 (e-PCR)
- UniSTS:44150

D17S1136 (e-PCR)
- UniSTS:473214

A004Q04 (e-PCR)
- UniSTS:11650

D5S1597E (e-PCR)
- UniSTS:151019

D11S3316 (e-PCR)
- UniSTS:152558

Other Names

EMX2 opposite strand/antisense RNA (non-protein coding)
empty spiracles homeobox 2 opposite strand
empty spiracles homolog 2 opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.