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Rpl7 ribosomal protein L7 [ Mus musculus (house mouse) ]

Gene ID: 19989, updated on 9-Dec-2024

Summary

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Official Symbol
Rpl7provided by MGI
Official Full Name
ribosomal protein L7provided by MGI
Primary source
MGI:MGI:98073
See related
Ensembl:ENSMUSG00000043716 AllianceGenome:MGI:98073
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpl7a; Surf-3
Summary
A structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within translation. Located in cytoplasm and ribosome. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several structures, including brain; early conceptus; female reproductive system; and liver. Orthologous to human RPL7 (ribosomal protein L7). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in CNS E11.5 (RPKM 611.3), liver E14 (RPKM 581.9) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Rpl7 in Genome Data Viewer
Location:
1 A3; 1 4.94 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (16171519..16174657, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (16101295..16104433, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930444P10 gene Neighboring gene STARR-seq mESC enhancer starr_00336 Neighboring gene predicted gene 7634 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16094431-16094614 Neighboring gene retinol dehydrogenase 10 (all-trans) Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16167808-16168008 Neighboring gene staufen double-stranded RNA binding protein 2 Neighboring gene predicted gene 7568

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A multigene family of intron lacking and containing genes, encoding for mouse ribosomal protein L7. Klein A, et al. Nucleic Acids Res, 1984 May 11. PMID 6328436, Free PMC Article
  2. Growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids with alternative 5'-untranslated regions are differentially expressed in mouse liver and placenta. Southard JN, et al. Endocrinology, 1995 Jul. PMID 7789316
  3. The mouse ribosomal protein L7 gene. Its primary structure and functional analysis of the promoter region. Meyuhas O, et al. J Biol Chem, 1990 Jul 15. PMID 2365680
  4. Expression of the growth hormone receptor and growth hormone-binding protein during pregnancy in the mouse. Cramer SD, et al. Endocrinology, 1992 Aug. PMID 1639029
  5. Isolation and characterization of BEN, a member of the TFII-I family of DNA-binding proteins containing distinct helix-loop-helix domains. Bayarsaihan D, et al. Proc Natl Acad Sci U S A, 2000 Jun 20. PMID 10861001, Free PMC Article

See all (66) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC102113

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 5S rRNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal large subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in A band ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
is_active_in presynapse NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
large ribosomal subunit protein uL30
Names
60S ribosomal protein L7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011291.5 → NP_035421.2  large ribosomal subunit protein uL30

    See identical proteins and their annotated locations for NP_035421.2

    Status: VALIDATED

    Source sequence(s)
    AK050656, BB839528, BY441493
    Consensus CDS
    CCDS14829.1
    UniProtKB/Swiss-Prot
    P14148, Q80UR0
    UniProtKB/TrEMBL
    Q3TK73, Q3UBI6, Q5M9N8
    Related
    ENSMUSP00000071616.7, ENSMUST00000058437.14
    Conserved Domains (1) summary
    TIGR01310
    Location:38 → 270
    uL30_euk; 60S ribosomal protein uL30, eukaryotic form

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    16171519..16174657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14148.2 GenPept UniProtKB/Swiss-Prot:P14148

Gene LinkOut

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