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Surf2 surfeit gene 2 [ Mus musculus (house mouse) ]

Gene ID: 20931, updated on 9-Dec-2024

Summary

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Official Symbol
Surf2provided by MGI
Official Full Name
surfeit gene 2provided by MGI
Primary source
MGI:MGI:98444
See related
Ensembl:ENSMUSG00000014873 AllianceGenome:MGI:98444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Surf-2
Summary
Predicted to be located in nuclear speck; nucleolus; and plasma membrane. Is expressed in embryo. Orthologous to human SURF2 (surfeit 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in liver E14 (RPKM 14.7), liver E14.5 (RPKM 14.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Surf2 in Genome Data Viewer
Location:
2 A3; 2 19.1 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26806420..26810199)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26916372..26920187)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7A Neighboring gene predicted gene, 24134 Neighboring gene predicted gene, 57689 Neighboring gene surfeit gene 1 Neighboring gene surfeit gene 4 Neighboring gene STARR-positive B cell enhancer ABC_E2605 Neighboring gene serine/threonine kinase-like domain containing 1 Neighboring gene REX4, 3'-5' exonuclease Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:26819876-26820059

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units. Williams TJ, et al. Mol Cell Biol, 1986 Dec. PMID 3025660, Free PMC Article
  2. One of the tightly clustered genes of the mouse surfeit locus is a highly expressed member of a multigene family whose other members are predominantly processed pseudogenes. Huxley C, et al. Mol Cell Biol, 1988 Sep. PMID 3221868, Free PMC Article
  3. Inherited prolonged bleeding time and platelet storage pool deficiency in the subtle gray (sut) mouse. Swank RT, et al. Lab Anim Sci, 1996 Feb. PMID 8699821
  4. The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA. Huxley C, et al. Mol Cell Biol, 1990 Feb. PMID 2300057, Free PMC Article
  5. Ribosomal protein L7a is encoded by a gene (Surf-3) within the tightly clustered mouse surfeit locus. Giallongo A, et al. Mol Cell Biol, 1989 Jan. PMID 2648130, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
surfeit locus protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001421138.1 → NP_001408067.1  surfeit locus protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL773563
    UniProtKB/TrEMBL
    Q3TA91

  2. NM_001421139.1 → NP_001408068.1  surfeit locus protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL773563

  3. NM_001421140.1 → NP_001408069.1  surfeit locus protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL773563

  4. NM_001421141.1 → NP_001408070.1  surfeit locus protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL773563

  5. NM_013678.4 → NP_038706.1  surfeit locus protein 2 isoform 1

    See identical proteins and their annotated locations for NP_038706.1

    Status: VALIDATED

    Source sequence(s)
    AL773563
    Consensus CDS
    CCDS15816.1
    UniProtKB/Swiss-Prot
    P09926
    UniProtKB/TrEMBL
    Q4VAF7
    Related
    ENSMUSP00000015017.8, ENSMUST00000015017.8
    Conserved Domains (1) summary
    pfam05477
    Location:5 → 241
    SURF2; Surfeit locus protein 2 (SURF2)

RNA

  1. NR_185250.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  2. NR_185251.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  3. NR_185252.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  4. NR_185253.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  5. NR_185254.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  6. NR_185255.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

  7. NR_185256.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL773563

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    26806420..26810199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P09926.1 GenPept UniProtKB/Swiss-Prot:P09926

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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