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Trp53-ps transformation related protein 53, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 22060, updated on 17-Aug-2024

Summary

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Official Symbol
Trp53-psprovided by MGI
Official Full Name
transformation related protein 53, pseudogeneprovided by MGI
Primary source
MGI:MGI:98835
See related
AllianceGenome:MGI:98835
Gene type
pseudo
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
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Genomic context

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See Trp53-ps in Genome Data Viewer
Location:
17 C; 17 28.3 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (54726625..54728264)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (54419597..54421236)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700025K24 gene Neighboring gene predicted gene, 52325 Neighboring gene STARR-seq mESC enhancer starr_42858 Neighboring gene STARR-seq mESC enhancer starr_42859 Neighboring gene myo-inositol 1-phosphate synthase A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_42860 Neighboring gene predicted gene, 26291

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome. Wang J, et al. Nat Commun, 2024 Jan 2. PMID 38167344, Free PMC Article
  2. p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism. Acosta J, et al. Nat Commun, 2023 Jul 21. PMID 37479684, Free PMC Article
  3. [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells]. Liu HY, et al. Sheng Li Xue Bao, 2023 Feb 25. PMID 36859831
  4. Analysis of recombinant DNA clones specific for the murine p53 cellular tumor antigen. Oren M, et al. EMBO J, 1983. PMID 6315396, Free PMC Article
  5. Regulation of the innate immune response and gut microbiome by p53. Khor AHP, et al. Cancer Sci, 2024 Jan. PMID 38050344, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
    Title: p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
  2. Kielin/chordin-like protein deficiency aggravates pressure overload-induced cardiac dysfunction and remodeling via P53/P21/CCNB1 signaling in mice.
    Title: Kielin/chordin-like protein deficiency aggravates pressure overload-induced cardiac dysfunction and remodeling via P53/P21/CCNB1 signaling in mice.
  3. CK1alpha deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3beta pathway and inhibiting Foxa2 expression through p53 pathwaydagger.
    Title: CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
  4. Regulation of the innate immune response and gut microbiome by p53.
    Title: Regulation of the innate immune response and gut microbiome by p53.
  5. p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.
    Title: p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.
  6. HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
    Title: HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
  7. Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/beta-catenin signaling.
    Title: Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.
  8. p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism.
    Title: p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism.
  9. E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.
    Title: E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.
  10. [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells].
    Title: [Effects and mechanism of p53 gene deletion on energy metabolism during the pluripotent transformation of spermatogonial stem cells].
Submit: New GeneRIF Correction See all GeneRIFs (12)

General gene information

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Markers

Other Names

  • p53-variant

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001473.4 

    Range
    101..1740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    54726625..54728264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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