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Zfp341 zinc finger protein 341 [ Mus musculus (house mouse) ]

Gene ID: 228807, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp341provided by MGI
Official Full Name
zinc finger protein 341provided by MGI
Primary source
MGI:MGI:2682937
See related
Ensembl:ENSMUSG00000059842 AllianceGenome:MGI:2682937
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf341
Summary
Predicted to enable DNA-binding transcription activator activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in central nervous system; female associated reproductive structure; ovary; tooth; and urethra of female. Human ortholog(s) of this gene implicated in hyper IgE recurrent infection syndrome 3. Orthologous to human ZNF341 (zinc finger protein 341). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 5.0), CNS E18 (RPKM 4.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp341 in Genome Data Viewer
Location:
2 H1; 2 76.79 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (154453736..154488741)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (154611816..154646821)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39963 Neighboring gene STARR-seq mESC enhancer starr_06130 Neighboring gene peroxisomal membrane protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E228 Neighboring gene predicted gene 14198 Neighboring gene STARR-positive B cell enhancer ABC_E7873 Neighboring gene STARR-positive B cell enhancer ABC_E6003 Neighboring gene charged multivesicular body protein 4B Neighboring gene RIKEN cDNA 9030607L20 gene Neighboring gene ribisomal protein L5, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Accelerating functional gene discovery in osteoarthritis. Butterfield NC, et al. Nat Commun, 2021 Jan 20. PMID 33473114, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

General gene information

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Homology

Clone Names

  • MGC73471

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription activator activity ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 341

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199304.1 → NP_955008.2  zinc finger protein 341

    See identical proteins and their annotated locations for NP_955008.2

    Status: PROVISIONAL

    Source sequence(s)
    BC057098
    Consensus CDS
    CCDS16937.1
    UniProtKB/TrEMBL
    A2AVM0, Q6PGC9
    Related
    ENSMUSP00000080596.7, ENSMUST00000081926.13
    Conserved Domains (5) summary
    COG5048
    Location:321 → 726
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:565 → 585
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:539 → 561
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:321 → 342
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:334 → 359
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    154453736..154488741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161505.1 → XP_036017398.1  zinc finger protein 341 isoform X1

    UniProtKB/TrEMBL
    A2AVM0
    Conserved Domains (3) summary
    COG5048
    Location:313 → 718
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:557 → 577
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:531 → 553
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_004940133.1 RNA Sequence

  2. XR_374456.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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