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Prpf38a PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [ Mus musculus (house mouse) ]

Gene ID: 230596, updated on 18-Sep-2024

Summary

Official Symbol
Prpf38aprovided by MGI
Official Full Name
PRP38 pre-mRNA processing factor 38 (yeast) domain containing Aprovided by MGI
Primary source
MGI:MGI:1916962
See related
Ensembl:ENSMUSG00000063800 AllianceGenome:MGI:1916962
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410002M20Rik
Summary
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of U2-type precatalytic spliceosome. Is expressed in lower jaw incisor; submandibular gland primordium; upper jaw incisor; and vibrissa. Orthologous to human PRPF38A (pre-mRNA processing factor 38A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 34.5), CNS E14 (RPKM 17.5) and 16 other tissues See more
Orthologs
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Genomic context

See Prpf38a in Genome Data Viewer
Location:
4 C7; 4 50.64 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108422064..108436533, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108564867..108579336, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene terminal uridylyl transferase 4 Neighboring gene predicted gene, 25827 Neighboring gene predicted gene, 22345 Neighboring gene STARR-positive B cell enhancer ABC_E1036 Neighboring gene origin recognition complex, subunit 1 Neighboring gene predicted gene 12743 Neighboring gene coiled-coil and C2 domain containing 1B Neighboring gene zinc finger, FYVE domain containing 9

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type precatalytic spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pre-mRNA-splicing factor 38A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172697.3NP_766285.2  pre-mRNA-splicing factor 38A

    See identical proteins and their annotated locations for NP_766285.2

    Status: VALIDATED

    Source sequence(s)
    AV323663, BC024734, BC059875, BY283675
    Consensus CDS
    CCDS18452.1
    UniProtKB/Swiss-Prot
    Q4FK66, Q6PB58, Q8BVY2
    UniProtKB/TrEMBL
    B2RTE3
    Related
    ENSMUSP00000078207.6, ENSMUST00000079213.6
    Conserved Domains (1) summary
    pfam03371
    Location:10172
    PRP38; PRP38 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    108422064..108436533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)