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Gxylt2 glucoside xylosyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 232313, updated on 9-Dec-2024

Summary

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Official Symbol
Gxylt2provided by MGI
Official Full Name
glucoside xylosyltransferase 2provided by MGI
Primary source
MGI:MGI:2682940
See related
Ensembl:ENSMUSG00000030074 AllianceGenome:MGI:2682940
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm152; Glt8d4
Summary
Predicted to enable UDP-xylosyltransferase activity. Predicted to be involved in O-glycan processing. Predicted to be located in membrane. Is expressed in aorta; embryo mesenchyme; incisor; and musculoskeletal system. Orthologous to human GXYLT2 (glucoside xylosyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in ovary adult (RPKM 8.5), limb E14.5 (RPKM 8.0) and 13 other tissues See more
Orthologs
human all
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Genomic context

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See Gxylt2 in Genome Data Viewer
Location:
6 D3; 6 46.9 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (100681638..100787738)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (100704672..100810888)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700049E22 gene Neighboring gene STARR-seq mESC enhancer starr_16870 Neighboring gene SHQ1 homolog (S. cerevisiae) Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr6:100621045-100621346 Neighboring gene high mobility group box 3 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1325 Neighboring gene STARR-positive B cell enhancer ABC_E2197 Neighboring gene STARR-seq mESC enhancer starr_16873 Neighboring gene protein phosphatase 4, regulatory subunit 2 Neighboring gene STARR-seq mESC enhancer starr_16877 Neighboring gene STARR-seq mESC enhancer starr_16880 Neighboring gene transmembrane protein 258 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each. Dogar AM, et al. PLoS One, 2018. PMID 30418981, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC59592

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-xylosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-xylosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables UDP-xylosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in O-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in O-glycan processing ISO
Inferred from Sequence Orthology
more info
  
involved_in O-glycan processing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucoside xylosyltransferase 2
Names
glycosyltransferase 8 domain containing 4
glycosyltransferase 8 domain-containing protein 4
NP_941014.1
XP_006506070.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198612.2 → NP_941014.1  glucoside xylosyltransferase 2

    See identical proteins and their annotated locations for NP_941014.1

    Status: PROVISIONAL

    Source sequence(s)
    AC121925, AC155648
    Consensus CDS
    CCDS20390.1
    UniProtKB/Swiss-Prot
    Q810K9
    Related
    ENSMUSP00000032157.8, ENSMUST00000032157.9
    Conserved Domains (2) summary
    cd06430
    Location:111 → 414
    GT8_like_2; GT8_like_2 represents a subfamily of GT8 with unknown function
    COG1442
    Location:127 → 396
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    100681638..100787738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506007.5 → XP_006506070.1  glucoside xylosyltransferase 2 isoform X1

    Conserved Domains (2) summary
    PHA03247
    Location:30 → 110
    PHA03247; large tegument protein UL36; Provisional
    cl11394
    Location:111 → 370
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q810K9.1 GenPept UniProtKB/Swiss-Prot:Q810K9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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