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ADGRL2 adhesion G protein-coupled receptor L2 [ Homo sapiens (human) ]

Gene ID: 23266, updated on 10-Dec-2024

Summary

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Official Symbol
ADGRL2provided by HGNC
Official Full Name
adhesion G protein-coupled receptor L2provided by HGNC
Primary source
HGNC:HGNC:18582
See related
Ensembl:ENSG00000117114 MIM:607018; AllianceGenome:HGNC:18582
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CL2; LEC1; CIRL2; LPHH1; LPHN2
Summary
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Expression
Ubiquitous expression in thyroid (RPKM 16.1), lung (RPKM 14.8) and 23 other tissues See more
Orthologs
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Genomic context

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See ADGRL2 in Genome Data Viewer
Location:
1p31.1
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (81306132..81993932)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (81143677..81831513)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (81771817..82459616)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985018 Neighboring gene NANOG hESC enhancer GRCh37_chr1:81771994-81772586 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:81777641-81778142 Neighboring gene RN7SK pseudogene 247 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:81778143-81778642 Neighboring gene Sharpr-MPRA regulatory region 14351 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1240 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:81923876-81924376 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene 14 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:81935555-81936062 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:81936063-81936570 Neighboring gene Sharpr-MPRA regulatory region 8606 Neighboring gene uncharacterized LOC101927434 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:82009398-82010005 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:82013019-82013798 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1007 Neighboring gene ARID3B pseudogene 1 Neighboring gene mediator complex subunit 28 pseudogene 8 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr1:82147966-82148534 Neighboring gene ribosomal protein S20 pseudogene 7 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:82269743-82270385 Neighboring gene ST13, Hsp70 interacting protein pseudogene 20 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:82314353-82315135 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:82533259-82533822 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_9174 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:82601932-82602446 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:82602447-82602960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:82716029-82716528 Neighboring gene uncharacterized LOC124904204 Neighboring gene uncharacterized LOC105378814

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions. Tanaka K, et al. EMBO J, 2024 Aug. PMID 38886581, Free PMC Article
  2. Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer. White GR, et al. Oncogene, 1998 Dec 31. PMID 10030676
  3. Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines. White GR, et al. Biochim Biophys Acta, 2000 Apr 25. PMID 10760572
  4. Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK. Lee CS, et al. Stem Cell Reports, 2021 Apr 13. PMID 33798451, Free PMC Article
  5. A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis. Vezain M, et al. Acta Neuropathol Commun, 2018 Oct 19. PMID 30340542, Free PMC Article

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions.
    Title: Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions.
  2. Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK.
    Title: Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK.
  3. LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion.
    Title: LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion.
  4. The results of this study suggest that this ADGRL2 variation impedes the proper development of the cerebellum resulting in RES which is thought to occur when the cerebellar primordium develops and probably results from abnormal function of genes expressed during initial patterning of the mesencephalon-rhombencephalon
    Title: A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.
EBI GWAS Catalog
Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
EBI GWAS Catalog
UGT1A1 is a major locus influencing bilirubin levels in African Americans.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables latrotoxin receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
adhesion G protein-coupled receptor L2
Names
calcium-independent alpha-latrotoxin receptor 2
latrophilin homolog 1
latrophilin-2
lectomedin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001297704.3 → NP_001284633.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001284633.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 5. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 4. Variants 1, 2, 8, 18, and 19 all encode the same isoform (1).
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS689.1
    UniProtKB/TrEMBL
    A0A6I8PRM6
    Related
    ENSP00000353006.2, ENST00000359929.7
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:831 → 1088
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  2. NM_001297705.3 → NP_001284634.1  adhesion G protein-coupled receptor L2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001284634.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon and contains two alternate exons in the 3' coding region, which results in a frameshift, compared to variant 5. The encoded isoform (2) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 4.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS72811.1
    UniProtKB/TrEMBL
    A0A6I8PRQ0
    Related
    ENSP00000359750.1, ENST00000370715.5
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam00002
    Location:832 → 1067
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1162
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:539 → 745
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  3. NM_001297706.3 → NP_001284635.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001284635.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two alternate exons compared to variant 5. The encoded isoform (3) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 4.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS76174.1
    UniProtKB/TrEMBL
    A0A6I8PRQ0
    Related
    ENSP00000359748.1, ENST00000370713.5
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam00002
    Location:832 → 1067
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1120
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:539 → 745
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  4. NM_001330645.3 → NP_001317574.1  adhesion G protein-coupled receptor L2 isoform 4 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variant 17, encodes isoform 4.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS81345.1
    UniProtKB/TrEMBL
    B1ALU3
    Related
    ENSP00000501462.1, ENST00000674419.1
    Conserved Domains (7) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:844 → 1101
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1416
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  5. NM_001350698.2 → NP_001337627.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 9, 10, and 16, encodes isoform 5.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1463
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  6. NM_001350699.2 → NP_001337628.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variant 21, encodes isoform 6.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS90990.1
    UniProtKB/TrEMBL
    A0A6I8PIV6, A0A6I8PRQ0
    Related
    ENSP00000501484.1, ENST00000674442.1
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1162
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833 → 858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:831 → 1088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  7. NM_001366002.2 → NP_001352931.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 1, 2, 18, and 19, encodes isoform 1.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS689.1
    UniProtKB/TrEMBL
    A0A6I8PRM6
    Related
    ENSP00000501431.1, ENST00000674393.1
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:831 → 1088
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  8. NM_001366003.2 → NP_001352932.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 6, 10 and 16, encodes isoform 5.
    Source sequence(s)
    AC093154, AC095035, AC113949, AL138799, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1463
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  9. NM_001366004.2 → NP_001352933.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 6, 9, and 16, encodes isoform 5.
    Source sequence(s)
    AC093154, AC095035, AC113949, AL138799, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1463
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  10. NM_001366005.2 → NP_001352934.1  adhesion G protein-coupled receptor L2 isoform 7 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variant 12, encodes isoform 7.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS90986.1
    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A8I5KUX3
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1469
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  11. NM_001366006.2 → NP_001352935.1  adhesion G protein-coupled receptor L2 isoform 7 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variant 11, encodes isoform 7.
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS90986.1
    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A8I5KUX3
    Related
    ENSP00000509478.1, ENST00000686636.1
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1469
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  12. NM_001366007.2 → NP_001352936.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRQ0
    Related
    ENSP00000501543.1, ENST00000674489.1
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1119 → 1227
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd16006
    Location:851 → 875
    7tmB2_Latrophilin-2; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1120
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  13. NM_001366008.2 → NP_001352937.1  adhesion G protein-coupled receptor L2 isoform 9 precursor

    Status: REVIEWED

    Source sequence(s)
    AC093154, AC095035, AC113949, AL138799, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRQ0
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1212
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  14. NM_001366009.2 → NP_001352938.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS90988.1
    UniProtKB/TrEMBL
    A0A6I8PLG0, A0A6I8PRQ0
    Related
    ENSP00000501532.1, ENST00000674208.1
    Conserved Domains (8) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1175
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:847 → 871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:844 → 1101
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  15. NM_001393349.1 → NP_001380278.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: REVIEWED

    Source sequence(s)
    AC093154, AC095035, AC113949, AL138799, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Related
    ENSP00000359760.1, ENST00000370725.5
    Conserved Domains (7) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    cd16006
    Location:848 → 1105
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1463
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain

  16. NM_001393350.1 → NP_001380279.1  adhesion G protein-coupled receptor L2 isoform 4 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS81345.1
    UniProtKB/TrEMBL
    B1ALU3
    Conserved Domains (7) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:844 → 1101
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1416
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  17. NM_001393351.1 → NP_001380280.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS689.1
    UniProtKB/TrEMBL
    A0A6I8PRM6
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:831 → 1088
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  18. NM_001393352.1 → NP_001380281.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS689.1
    UniProtKB/TrEMBL
    A0A6I8PRM6
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:831 → 1088
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  19. NM_001393353.1 → NP_001380282.1  adhesion G protein-coupled receptor L2 isoform 11 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    UniProtKB/TrEMBL
    A0A6I8PRQ0
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1162
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833 → 858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:831 → 1088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  20. NM_001393354.1 → NP_001380283.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS90990.1
    UniProtKB/TrEMBL
    A0A6I8PIV6, A0A6I8PRQ0
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1162
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833 → 858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:831 → 1088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  21. NM_012302.5 → NP_036434.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_036434.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 5. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 4. Variants 1, 2, 8, 18, and 19 all encode the same isoform (1).
    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705
    Consensus CDS
    CCDS689.1
    UniProtKB/TrEMBL
    A0A6I8PRM6
    Related
    ENSP00000322270.6, ENST00000319517.10
    Conserved Domains (7) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:831 → 1088
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

RNA

  1. NR_171658.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC113949, AL157903, AL358939, AL359705

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    81306132..81993932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047416152.1 → XP_047272108.1  adhesion G protein-coupled receptor L2 isoform X6

    UniProtKB/TrEMBL
    A0A6I8PLG0, A0A6I8PRQ0

  2. XM_047416118.1 → XP_047272074.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2
    Related
    ENSP00000359758.1, ENST00000370723.5

  3. XM_047416159.1 → XP_047272115.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  4. XM_047416140.1 → XP_047272096.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  5. XM_047416096.1 → XP_047272052.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  6. XM_024454355.2 → XP_024310123.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3
    Related
    ENSP00000359765.1, ENST00000370730.5
    Conserved Domains (7) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    cd16006
    Location:844 → 1101
    7tmB2_Latrophilin-2; Latrophilin-2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1416
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  7. XM_047416129.1 → XP_047272085.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  8. XM_047416124.1 → XP_047272080.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  9. XM_047416170.1 → XP_047272126.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  10. XM_047416146.1 → XP_047272102.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  11. XM_017000784.2 → XP_016856273.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (8) summary
    smart00303
    Location:789 → 841
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:470 → 534
    HormR; Domain present in hormone receptors
    COG1266
    Location:918 → 1092
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:850 → 1085
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1105 → 1464
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:544 → 763
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:143 → 399
    OLF; Olfactomedin-like domain

  12. XM_047416105.1 → XP_047272061.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Related
    ENSP00000359752.3, ENST00000370717.6

  13. XM_005270668.3 → XP_005270725.1  adhesion G protein-coupled receptor L2 isoform X3

    See identical proteins and their annotated locations for XP_005270725.1

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2
    Related
    ENSP00000501324.1, ENST00000674209.1
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    COG1266
    Location:900 → 1074
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:832 → 1067
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1446
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:539 → 745
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  14. XM_047416176.1 → XP_047272132.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  15. XM_047416098.1 → XP_047272054.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  16. XM_047416104.1 → XP_047272060.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  17. XM_047416132.1 → XP_047272088.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  18. XM_047416126.1 → XP_047272082.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  19. XM_047416180.1 → XP_047272136.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  20. XM_006710489.4 → XP_006710552.1  adhesion G protein-coupled receptor L2 isoform X1

    See identical proteins and their annotated locations for XP_006710552.1

    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (8) summary
    smart00303
    Location:789 → 841
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:470 → 534
    HormR; Domain present in hormone receptors
    COG1266
    Location:918 → 1092
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:850 → 1085
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1105 → 1464
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:544 → 763
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:143 → 399
    OLF; Olfactomedin-like domain

  21. XM_047416115.1 → XP_047272071.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  22. XM_047416156.1 → XP_047272112.1  adhesion G protein-coupled receptor L2 isoform X6

    UniProtKB/TrEMBL
    A0A6I8PLG0, A0A6I8PRQ0

  23. XM_006710488.3 → XP_006710551.1  adhesion G protein-coupled receptor L2 isoform X1

    See identical proteins and their annotated locations for XP_006710551.1

    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (8) summary
    smart00303
    Location:789 → 841
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:470 → 534
    HormR; Domain present in hormone receptors
    COG1266
    Location:918 → 1092
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:850 → 1085
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1105 → 1464
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:544 → 763
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:143 → 399
    OLF; Olfactomedin-like domain

  24. XM_047416102.1 → XP_047272058.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  25. XM_047416121.1 → XP_047272077.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  26. XM_006710485.4 → XP_006710548.1  adhesion G protein-coupled receptor L2 isoform X1

    See identical proteins and their annotated locations for XP_006710548.1

    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (8) summary
    smart00303
    Location:789 → 841
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:470 → 534
    HormR; Domain present in hormone receptors
    COG1266
    Location:918 → 1092
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:850 → 1085
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1105 → 1464
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:544 → 763
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:143 → 399
    OLF; Olfactomedin-like domain

  27. XM_005270666.5 → XP_005270723.1  adhesion G protein-coupled receptor L2 isoform X2

    See identical proteins and their annotated locations for XP_005270723.1

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Conserved Domains (8) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    COG1266
    Location:913 → 1087
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam00002
    Location:845 → 1080
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1459
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:539 → 758
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain

  28. XM_047416128.1 → XP_047272084.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  29. XM_047416119.1 → XP_047272075.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  30. XM_047416164.1 → XP_047272120.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  31. XM_047416145.1 → XP_047272101.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  32. XM_047416092.1 → XP_047272048.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  33. XM_047416109.1 → XP_047272065.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  34. XM_047416130.1 → XP_047272086.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  35. XM_047416120.1 → XP_047272076.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  36. XM_047416178.1 → XP_047272134.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  37. XM_047416150.1 → XP_047272106.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  38. XM_047416099.1 → XP_047272055.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  39. XM_047416110.1 → XP_047272066.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0
    Related
    ENSP00000359763.1, ENST00000370728.5

  40. XM_047416136.1 → XP_047272092.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  41. XM_047416148.1 → XP_047272104.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    81143677..81831513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054335445.1 → XP_054191420.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  2. XM_054335478.1 → XP_054191453.1  adhesion G protein-coupled receptor L2 isoform X11

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  3. XM_054335464.1 → XP_054191439.1  adhesion G protein-coupled receptor L2 isoform X9

    UniProtKB/TrEMBL
    B1ALU3

  4. XM_054335457.1 → XP_054191432.1  adhesion G protein-coupled receptor L2 isoform X8

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  5. XM_054335481.1 → XP_054191456.1  adhesion G protein-coupled receptor L2 isoform X12

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  6. XM_054335471.1 → XP_054191446.1  adhesion G protein-coupled receptor L2 isoform X10

    UniProtKB/TrEMBL
    A0A6I8PRM6

  7. XM_054335479.1 → XP_054191454.1  adhesion G protein-coupled receptor L2 isoform X6

    UniProtKB/TrEMBL
    A0A6I8PLG0, A0A6I8PRQ0

  8. XM_054335470.1 → XP_054191445.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  9. XM_054335458.1 → XP_054191433.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  10. XM_054335482.1 → XP_054191457.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  11. XM_054335472.1 → XP_054191447.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  12. XM_054335450.1 → XP_054191425.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  13. XM_054335466.1 → XP_054191441.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  14. XM_054335476.1 → XP_054191451.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  15. XM_054335477.1 → XP_054191452.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  16. XM_054335451.1 → XP_054191426.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  17. XM_054335468.1 → XP_054191443.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  18. XM_054335474.1 → XP_054191449.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  19. XM_054335452.1 → XP_054191427.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  20. XM_054335454.1 → XP_054191429.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  21. XM_054335459.1 → XP_054191434.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  22. XM_054335485.1 → XP_054191460.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  23. XM_054335467.1 → XP_054191442.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  24. XM_054335462.1 → XP_054191437.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  25. XM_054335484.1 → XP_054191459.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  26. XM_054335456.1 → XP_054191431.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  27. XM_054335480.1 → XP_054191455.1  adhesion G protein-coupled receptor L2 isoform X6

    UniProtKB/TrEMBL
    A0A6I8PLG0, A0A6I8PRQ0

  28. XM_054335449.1 → XP_054191424.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  29. XM_054335447.1 → XP_054191422.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  30. XM_054335453.1 → XP_054191428.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  31. XM_054335460.1 → XP_054191435.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  32. XM_054335446.1 → XP_054191421.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  33. XM_054335448.1 → XP_054191423.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PRJ0

  34. XM_054335455.1 → XP_054191430.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    A5XEI2, B1ALT8, B1ALT9, B1ALU0, B1ALU2, B1ALU4, B1ALU5, B1ALU6, O94882, O95490, Q5VX76, Q9UKY5, Q9UKY6
    UniProtKB/TrEMBL
    A0A6I8PRJ0

  35. XM_054335461.1 → XP_054191436.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  36. XM_054335463.1 → XP_054191438.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PRJ0, A0A6I8PTT2

  37. XM_054335465.1 → XP_054191440.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  38. XM_054335469.1 → XP_054191444.1  adhesion G protein-coupled receptor L2 isoform X4

    UniProtKB/TrEMBL
    B1ALU3

  39. XM_054335483.1 → XP_054191458.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  40. XM_054335486.1 → XP_054191461.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A6I8PRQ0

  41. XM_054335473.1 → XP_054191448.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6

  42. XM_054335475.1 → XP_054191450.1  adhesion G protein-coupled receptor L2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8PRM6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O95490.2 GenPept UniProtKB/Swiss-Prot:O95490

Gene LinkOut

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