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Hykk hydroxylysine kinase 1 [ Mus musculus (house mouse) ]

Gene ID: 235386, updated on 9-Aug-2024

Summary

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Official Symbol
Hykkprovided by MGI
Official Full Name
hydroxylysine kinase 1provided by MGI
Primary source
MGI:MGI:2443139
See related
Ensembl:ENSMUSG00000035878 AllianceGenome:MGI:2443139
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Agphd1; C630028N24Rik
Summary
Predicted to enable hydroxylysine kinase activity. Predicted to be located in cytoplasm. Orthologous to human HYKK (hydroxylysine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 15.0), liver adult (RPKM 4.3) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Hykk in Genome Data Viewer
Location:
9 B; 9 29.84 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54824574..54857208)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54917290..54949924)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RAB7, member RAS oncogene family, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_24177 Neighboring gene STARR-seq mESC enhancer starr_24179 Neighboring gene STARR-positive B cell enhancer ABC_E2292 Neighboring gene iron responsive element binding protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E1787 Neighboring gene STARR-positive B cell enhancer ABC_E6734 Neighboring gene cDNA sequence AY074887 Neighboring gene proteasome subunit alpha 4 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 5 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables amino acid kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydroxylysine kinase activity ISO
Inferred from Sequence Orthology
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hydroxylysine kinase
Names
5-hydroxy-L-lysine kinase
aminoglycoside phosphotransferase domain containing 1
aminoglycoside phosphotransferase domain-containing protein 1
NP_796325.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177351.4 → NP_796325.2  hydroxylysine kinase

    See identical proteins and their annotated locations for NP_796325.2

    Status: VALIDATED

    Source sequence(s)
    AC161264, AK162425
    Consensus CDS
    CCDS23197.1
    UniProtKB/Swiss-Prot
    Q3TQ48, Q3TRW8, Q3UU28, Q5U5V2, Q8C3L8
    Related
    ENSMUSP00000039980.8, ENSMUST00000039742.8
    Conserved Domains (2) summary
    COG2334
    Location:11 → 351
    SrkA; Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist [Signal transduction mechanisms]
    cl21453
    Location:33 → 311
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    54824574..54857208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U5V2.2 GenPept UniProtKB/Swiss-Prot:Q5U5V2

Gene LinkOut

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