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Tceal1 transcription elongation factor A (SII)-like 1 [ Mus musculus (house mouse) ]

Gene ID: 237052, updated on 9-Dec-2024

Summary

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Official Symbol
Tceal1provided by MGI
Official Full Name
transcription elongation factor A (SII)-like 1provided by MGI
Primary source
MGI:MGI:2385317
See related
Ensembl:ENSMUSG00000049536 AllianceGenome:MGI:2385317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P21; SIIR; pp21; 0610011M09Rik
Summary
Predicted to be located in nucleoplasm. Is expressed in several structures, including foregut; ganglia; lung; remnant of Rathke's pouch; and sensory organ. Orthologous to human TCEAL1 (transcription elongation factor A like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in CNS E18 (RPKM 10.2), frontal lobe adult (RPKM 9.5) and 19 other tissues See more
Orthologs
human all
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Genomic context

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See Tceal1 in Genome Data Viewer
Location:
X F1; X 59.1 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135608731..135610622)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136707982..136709873)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A (SII)-like 3 Neighboring gene acyl-protein thioesterase 1 pseudogene Neighboring gene predicted gene, 39536 Neighboring gene STARR-seq mESC enhancer starr_47978 Neighboring gene STARR-positive B cell enhancer ABC_E3262 Neighboring gene STARR-positive B cell enhancer ABC_E11056 Neighboring gene mortality factor 4 like 2 Neighboring gene cDNA sequence BC065397 Neighboring gene glycine receptor, alpha 4 subunit Neighboring gene predicted gene, 54085

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
  2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
  3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  4. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC18752, MGC102312

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transcription elongation factor A protein-like 1
Names
TCEA-like protein 1
transcription elongation factor S-II protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356367.1 → NP_001343296.1  transcription elongation factor A protein-like 1

    Status: VALIDATED

    Source sequence(s)
    AL671887, CK618090, DV057188
    Consensus CDS
    CCDS30421.1
    UniProtKB/Swiss-Prot
    Q921P9
    Conserved Domains (1) summary
    pfam04538
    Location:93 → 165
    BEX; Brain expressed X-linked like family

  2. NM_146236.2 → NP_666348.1  transcription elongation factor A protein-like 1

    See identical proteins and their annotated locations for NP_666348.1

    Status: VALIDATED

    Source sequence(s)
    AL671887, CK618090, DV051075
    Consensus CDS
    CCDS30421.1
    UniProtKB/Swiss-Prot
    Q921P9
    Related
    ENSMUSP00000061875.6, ENSMUST00000055104.6
    Conserved Domains (1) summary
    pfam04538
    Location:93 → 165
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    135608731..135610622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251327.1 → XP_030107187.1  transcription elongation factor A protein-like 1 isoform X1

    UniProtKB/Swiss-Prot
    Q921P9
    Conserved Domains (1) summary
    pfam04538
    Location:93 → 165
    BEX; Brain expressed X-linked like family

  2. XM_006528517.4 → XP_006528580.1  transcription elongation factor A protein-like 1 isoform X1

    See identical proteins and their annotated locations for XP_006528580.1

    UniProtKB/Swiss-Prot
    Q921P9
    Conserved Domains (1) summary
    pfam04538
    Location:93 → 165
    BEX; Brain expressed X-linked like family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q921P9.1 GenPept UniProtKB/Swiss-Prot:Q921P9

Gene LinkOut

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