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Zfp867 zinc finger protein 867 [ Mus musculus (house mouse) ]

Gene ID: 237775, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp867provided by MGI
Official Full Name
zinc finger protein 867provided by MGI
Primary source
MGI:MGI:2681848
See related
Ensembl:ENSMUSG00000054519 AllianceGenome:MGI:2681848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF136 (zinc finger protein 136) and ZNF627 (zinc finger protein 627). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in CNS E18 (RPKM 3.6), CNS E14 (RPKM 3.2) and 23 other tissues See more
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Genomic context

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See Zfp867 in Genome Data Viewer
Location:
11 B1.3; 11 37.71 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59352023..59363353, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59461197..59472527, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_29623 Neighboring gene serine protease 38 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:59198075-59198323 Neighboring gene predicted gene 15755 Neighboring gene synaptosomal-associated protein, 47 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:59263537-59263646 Neighboring gene STARR-seq mESC enhancer starr_29624 Neighboring gene jumonji domain containing 4 Neighboring gene ariadne homolog 2 pseudogene Neighboring gene zinc finger with KRAB and SCAN domains 17 Neighboring gene RIKEN cDNA 4933439C10 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC60963

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 867
Names
zinc finger protein LOC237775

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178417.3 → NP_848504.2  zinc finger protein 867

    Status: VALIDATED

    Source sequence(s)
    AK132062, AL592522
    Consensus CDS
    CCDS24769.1
    UniProtKB/TrEMBL
    E9Q2M4
    Related
    ENSMUSP00000050746.8, ENSMUST00000057799.8
    Conserved Domains (5) summary
    smart00349
    Location:12 → 52
    KRAB; krueppel associated box
    COG5048
    Location:119 → 431
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:207 → 227
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 51
    KRAB; KRAB box
    pfam13465
    Location:247 → 272
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    59352023..59363353 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248984.3 → XP_011247286.1  zinc finger protein 867 isoform X1

    Conserved Domains (3) summary
    sd00017
    Location:207 → 227
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:11 → 51
    KRAB; KRAB box
    pfam13465
    Location:247 → 272
    zf-H2C2_2; Zinc-finger double domain

  2. XM_030245963.1 → XP_030101823.1  zinc finger protein 867 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:14 → 326
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:102 → 122
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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