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Scart2 scavenger receptor family member expressed on T cells 2 [ Mus musculus (house mouse) ]

Gene ID: 244234, updated on 9-Aug-2024

Summary

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Official Symbol
Scart2provided by MGI
Official Full Name
scavenger receptor family member expressed on T cells 2provided by MGI
Primary source
MGI:MGI:2443685
See related
Ensembl:ENSMUSG00000054672 AllianceGenome:MGI:2443685
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5830411N06Rik
Summary
Acts upstream of or within gamma-delta T cell lineage commitment. Located in external side of plasma membrane. Is expressed in ileum; male reproductive gland or organ; and metanephros. Orthologous to human SCART1 (scavenger receptor family member expressed on T cells 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in thymus adult (RPKM 4.6), mammary gland adult (RPKM 0.9) and 1 other tissue See more
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Genomic context

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See Scart2 in Genome Data Viewer
Location:
7 F4; 7 85.29 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (139827192..139880647)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (140247279..140300734)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_20448 Neighboring gene olfactory receptor enhancer Fourni Neighboring gene olfactory receptor family 6 subfamily F member 2 Neighboring gene scavenger receptor family member expressed on T cells 1 Neighboring gene olfactory receptor family 6 subfamily B member 13 Neighboring gene predicted pseudogene 6314 Neighboring gene olfactory receptor family 13 subfamily A member 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. SCART scavenger receptors identify a novel subset of adult gammadelta T cells. Kisielow J, et al. J Immunol, 2008 Aug 1. PMID 18641307
  2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. described two novel surface receptors, SCART1 and SCART2
    Title: SCART scavenger receptors identify a novel subset of adult gammadelta T cells.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within gamma-delta T cell lineage commitment IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within interleukin-17 production IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
scavenger receptor family member expressed on T cells 2
Names
mFLJ00268 protein
scavenger receptor protein family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128145.1 → NP_001121617.1  scavenger receptor family member expressed on T cells 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001121617.1

    Status: PROVISIONAL

    Source sequence(s)
    EF624463
    Consensus CDS
    CCDS52434.1
    UniProtKB/TrEMBL
    B3F5L5
    Related
    ENSMUSP00000091520.3, ENSMUST00000093984.3
    Conserved Domains (2) summary
    smart00202
    Location:551 → 651
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:162 → 233
    SRCR; Scavenger receptor cysteine-rich domain

  2. NM_001128146.1 → NP_001121618.1  scavenger receptor family member expressed on T cells 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001121618.1

    Status: PROVISIONAL

    Source sequence(s)
    EF624462
    Consensus CDS
    CCDS52433.1
    UniProtKB/TrEMBL
    B3F5L4
    Related
    ENSMUSP00000131905.2, ENSMUST00000164583.8
    Conserved Domains (2) summary
    smart00202
    Location:667 → 767
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:162 → 233
    SRCR; Scavenger receptor cysteine-rich domain

  3. NM_175533.3 → NP_780742.1  scavenger receptor family member expressed on T cells 2 isoform 3 precursor

    See identical proteins and their annotated locations for NP_780742.1

    Status: PROVISIONAL

    Source sequence(s)
    AK040624
    UniProtKB/TrEMBL
    Q8C9T4
    Related
    ENSMUST00000059882.13
    Conserved Domains (2) summary
    smart00202
    Location:239 → 336
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:243 → 336
    SRCR; Scavenger receptor cysteine-rich domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    139827192..139880647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006536189.1 → XP_006536252.1  scavenger receptor family member expressed on T cells 2 isoform X2

    See identical proteins and their annotated locations for XP_006536252.1

    UniProtKB/TrEMBL
    B3F5L4
    Conserved Domains (2) summary
    smart00202
    Location:667 → 767
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:162 → 233
    SRCR; Scavenger receptor cysteine-rich domain

  2. XM_006536186.1 → XP_006536249.1  scavenger receptor family member expressed on T cells 2 isoform X1

    See identical proteins and their annotated locations for XP_006536249.1

    UniProtKB/TrEMBL
    B3F5L5
    Conserved Domains (2) summary
    smart00202
    Location:551 → 651
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:162 → 233
    SRCR; Scavenger receptor cysteine-rich domain

RNA

  1. XR_389955.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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