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h2az2a H2A.Z variant histone 2a [ Danio rerio (zebrafish) ]

Gene ID: 252913, updated on 2-Nov-2024

Summary

Official Symbol
h2az2aprovided by ZNC
Official Full Name
H2A.Z variant histone 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020717-1
See related
Ensembl:ENSDARG00000068820 AllianceGenome:ZFIN:ZDB-GENE-020717-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
h2afv; h2afz; h2aza; h2afva; H2A.F/Z
Summary
Predicted to be a structural constituent of chromatin. Acts upstream of or within positive regulation of melanocyte differentiation. Predicted to be located in chromosome and membrane. Predicted to be part of nucleosome. Predicted to be active in nucleus. Is expressed in ovarian follicle. Orthologous to human H2AZ2 (H2A.Z variant histone 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See h2az2a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13647316..13652687)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13147044..13152470)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885516 Neighboring gene purine-rich element binding protein Ba Neighboring gene neuronal intermediate filament family member 1 Neighboring gene MAX dimerization protein 1 Neighboring gene uncharacterized LOC137495562

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within positive regulation of melanocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
histone H2A.V
Names
H2A histone family, member V
H2A histone family, member Va
H2A histone family, member Z

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153644.1NP_705930.1  histone H2A.V

    See identical proteins and their annotated locations for NP_705930.1

    Status: PROVISIONAL

    Source sequence(s)
    AF414110
    UniProtKB/Swiss-Prot
    Q71PD7
    UniProtKB/TrEMBL
    A2BFY9
    Related
    ENSDARP00000090434.4, ENSDART00000099660.6
    Conserved Domains (1) summary
    PLN00154
    Location:6121
    PLN00154; histone H2A; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    13647316..13652687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)