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mcb1 mini-chromosome maintenance complex-binding protein mcb1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542796, updated on 18-Sep-2024

Summary

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Official Symbol
mcb1
Official Full Name
mini-chromosome maintenance complex-binding protein mcb1
Primary source
PomBase:SPAC1687.04
Locus tag
SPOM_SPAC1687.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mcb1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (906797..908799)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CAAX prenyl protease Neighboring gene DNA replication factor C complex subunit Rfc4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SUMO E3 ligase Pli1 Neighboring gene ribosomal L28e protein family domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase. Ding L, et al. J Biol Chem, 2011 Sep 23. PMID 21813639, Free PMC Article
  2. Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex. Li JJ, et al. FEBS Lett, 2011 Dec 15. PMID 22036784
  3. The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication. Santosa V, et al. J Biol Chem, 2013 Mar 8. PMID 23322785, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results suggest that Mcb1 promotes efficient prereplicative complex (pre-RC) formation during DNA replication by regulating the minichromosome maintenance (MCM) complex.
    Title: The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic DNA replication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mini-chromosome maintenance complex-binding protein mcb1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    906797..908799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018518.3 → NP_593122.1  mini-chromosome maintenance complex-binding protein mcb1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593122.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94450
    Conserved Domains (1) summary
    pfam09739
    Location:44 → 485
    MCM_bind; Mini-chromosome maintenance replisome factor
Nucleotide Protein
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