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arb1 argonaute inhibitor protein 1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542862, updated on 22-Jun-2024

Summary

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Gene symbol
arb1
Gene description
argonaute inhibitor protein 1
Locus tag
SPOM_SPAC140.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
csp12
Old locus tag
SPAC140.03
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Genomic context

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See arb1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (1899966..1901605)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase iron-sulfur subunit protein Neighboring gene ncRNA Neighboring gene nucleolin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein ctr1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Small-RNA loading licenses Argonaute for assembly into a transcriptional silencing complex. Holoch D, et al. Nat Struct Mol Biol, 2015 Apr. PMID 25730778, Free PMC Article
  2. Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast. Buker SM, et al. Nat Struct Mol Biol, 2007 Mar. PMID 17310250
  3. RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5. Okazaki K, et al. Epigenetics Chromatin, 2018 Jun 4. PMID 29866182, Free PMC Article
  4. RNA interference regulates the cell cycle checkpoint through the RNA export factor, Ptr1, in fission yeast. Iida T, et al. Biochem Biophys Res Commun, 2012 Oct 12. PMID 22989756
  5. Argonaute and Triman generate dicer-independent priRNAs and mature siRNAs to initiate heterochromatin formation. Marasovic M, et al. Mol Cell, 2013 Oct 24. PMID 24095277

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables endoribonuclease inhibitor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ribonuclease inhibitor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in siRNA-mediated pericentric heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of ARC complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
NOT part_of pericentric heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
argonaute inhibitor protein 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1899966..1901605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018966.3 → NP_593532.1  argonaute inhibitor protein 1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593532.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7B8
    Conserved Domains (1) summary
    pfam09692
    Location:32 → 399
    Arb1; Argonaute siRNA chaperone (ARC) complex subunit Arb1
Nucleotide Protein
Heading Accession and Version

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