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aur1 inositol phosphorylceramide synthase Aur1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543632, updated on 22-Jun-2024

Summary

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Gene symbol
aur1
Gene description
inositol phosphorylceramide synthase Aur1
Locus tag
SPOM_SPAC3H8.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPAC3H8.06
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Genomic context

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See aur1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (598449..600805)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin ligase complex subunit Mms1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor Neighboring gene prefoldin subunit Pfd3 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  3. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables inositol phosphoceramide synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in inositol phosphoceramide metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sphingolipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus HDA PubMed 
is_active_in Golgi membrane IC
Inferred by Curator
more info
  
part_of inositol phosphoceramide synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
inositol phosphorylceramide synthase Aur1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    598449..600805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018398.3 → NP_592999.1  inositol phosphorylceramide synthase Aur1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592999.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P79014, Q10142
    Conserved Domains (2) summary
    COG0671
    Location:248 → 319
    PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
    cd03386
    Location:122 → 317
    PAP2_Aur1_like; PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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