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DHBVgp4 P-protein [ Duck hepatitis B virus ]

Gene ID: 2546414, updated on 18-Aug-2023

Summary

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Gene symbol
DHBVgp4
Gene description
P-protein
Locus tag
DHBVgp4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Duck hepatitis B virus (isolate: DHBVQCA34)
Lineage
Viruses; Retro-transcribing viruses; Hepadnaviridae; Avihepadnavirus
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Genomic context

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Sequence:
NC_001344.1 (170..2536)

NC_001344.1Genomic Context describing neighboring genes Neighboring gene secretory protein Neighboring gene nucleocapsid protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene pre-S protein Neighboring gene surface protein Neighboring gene secretory protein Neighboring gene nucleocapsid protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001344.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TP-RT domain interactions of duck hepatitis B virus reverse transcriptase in cis and in trans during protein-primed initiation of DNA synthesis in vitro. Boregowda RK, et al. J Virol, 2012 Jun. PMID 22514346, Free PMC Article
  2. Extensive mutagenesis of the conserved box E motif in duck hepatitis B virus P protein reveals multiple functions in replication and a common structure with the primer grip in HIV-1 reverse transcriptase. Wang YX, et al. J Virol, 2012 Jun. PMID 22514339, Free PMC Article
  3. RNA elements directing translation of the duck hepatitis B Virus polymerase via ribosomal shunting. Cao F, et al. J Virol, 2011 Jul. PMID 21507974, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The RT domain of reverse transcriptase could additionally use a separate TP or RT domain in trans as a primer.
    Title: TP-RT domain interactions of duck hepatitis B virus reverse transcriptase in cis and in trans during protein-primed initiation of DNA synthesis in vitro.
  2. The conserved box E motif in the P protein was critical for DHBV replication.
    Title: Extensive mutagenesis of the conserved box E motif in duck hepatitis B virus P protein reveals multiple functions in replication and a common structure with the primer grip in HIV-1 reverse transcriptase.
  3. Two RNA elements in the 5' portion of the mRNA were found to assist shunting and direct translation of reverse transcriptase (P)
    Title: RNA elements directing translation of the duck hepatitis B Virus polymerase via ribosomal shunting.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
P-protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001344.1 Reference assembly

    Range
    170..2536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_039822.1 P-protein [Duck hepatitis B virus]

    See identical proteins and their annotated locations for NP_039822.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P17192, Q66402, Q66403
    Conserved Domains (3) summary
    pfam00242
    Location:71 → 340
    DNA_pol_viral_N; DNA polymerase (viral) N-terminal domain
    pfam00336
    Location:579 → 775
    DNA_pol_viral_C; DNA polymerase (viral) C-terminal domain
    cl02808
    Location:401 → 565
    RT_like; RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...
Nucleotide Protein
Heading Accession and Version

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