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NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (HIV type 2; Human immunodeficiency virus type 2; Human immunodeficiency virus-2; human immunodeficiency virus type 2 HIV-2; human immunodeficiency virus type 2, HIV-2). [ Human immunodeficiency virus 2 ]

Gene ID: 2828721, updated on 20-May-2020

Summary

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Gene symbol
NEWENTRY
Gene description
Record to support submission of GeneRIFs for a gene not in Gene (HIV type 2; Human immunodeficiency virus type 2; Human immunodeficiency virus-2; human immunodeficiency virus type 2 HIV-2; human immunodeficiency virus type 2, HIV-2).
Gene type
other
Organism
Human immunodeficiency virus 2
Lineage
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus
Also known as
NEWENTRY
NEW
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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HIV-2 capsid sequences expressed high levels of susceptibility to hTRIM5alpha.
    Title: High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences.
  2. A strong association was found between HIV-2 phenotypic tropism and gp105 V3-loop sequences, allowing for the prediction of R5- and/or X4-tropic viruses in HIV-2 infection. [HIV-2 gp105 envelope glycoprotein]
    Title: Molecular determinants of HIV-2 R5-X4 tropism in the V3 loop: development of a new genotypic tool.
  3. Intrinsic HIV-2 integrase variation at "secondary" HIV-1 integrase inhibitor-resistance sites may affect the genetic barrier to HIV-2 INI resistance.[Integrase]
    Title: HIV-2 integrase variation in integrase inhibitor-naïve adults in Senegal, West Africa.
  4. Both the dimeric and folded monomeric forms of HIV-2 protease were characterized by solution NMR and compared with HIV-1 protease.[HIV-2 protease]
    Title: Revealing the dimer dissociation and existence of a folded monomer of the mature HIV-2 protease.
  5. gp105 suppresses activation of T cells through a monocyte-mediated mechanism. The TLR4 pathway is likely involved, since gp105 activates TLR4 signaling and induces TNF-alpha production by monocytes. gp105.
    Title: Monocyte-mediated T cell suppression by HIV-2 envelope proteins.
Submit: New GeneRIF Correction

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Research Materials