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Rpl3l ribosomal protein L3-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 287122, updated on 17-Aug-2024

Summary

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Official Symbol
Rpl3lprovided by RGD
Official Full Name
ribosomal protein L3-likeprovided by RGD
Primary source
RGD:1306315
See related
EnsemblRapid:ENSRNOG00000014641 AllianceGenome:RGD:1306315
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human RPL3L (ribosomal protein L3 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 655.9) and Heart (RPKM 287.5) See more
Orthologs
human mouse all
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Genomic context

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See Rpl3l in Genome Data Viewer
Location:
10q12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (14258446..14268989)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13753914..13764458)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14094769..14105312)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, H/ACA box 64 Neighboring gene ribosomal protein S2 Neighboring gene NADH:ubiquinone oxidoreductase subunit B10 Neighboring gene methionine sulfoxide reductase B1 Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. Odintsova TI, et al. J Protein Chem, 2003 Apr. PMID 12962325
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of myotube differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of striated muscle tissue development ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ribosomal protein uL3-like
Names
60S ribosomal protein L3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191589.1 → NP_001178518.1  ribosomal protein uL3-like

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    D4A9G1
    Related
    ENSRNOP00000019660.5, ENSRNOT00000019660.9
    Conserved Domains (2) summary
    PTZ00103
    Location:1 → 400
    PTZ00103; 60S ribosomal protein L3; Provisional
    cl00324
    Location:7 → 373
    RplC; Ribosomal protein L3 [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    14258446..14268989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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