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Bacc1 BPTF associated chromatin complex component 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287452, updated on 14-Nov-2024

Summary

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Official Symbol
Bacc1provided by RGD
Official Full Name
BPTF associated chromatin complex component 1provided by RGD
Primary source
RGD:1308134
See related
EnsemblRapid:ENSRNOG00000018829 AllianceGenome:RGD:1308134
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308134; C10h17orf49
Summary
Predicted to enable identical protein binding activity. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of MLL1 complex and NURF complex. Orthologous to human C17orf49 (chromosome 17 open reading frame 49). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 54.3), Heart (RPKM 45.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Bacc1 in Genome Data Viewer
Location:
10q24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55450648..55453409, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54951991..54954756, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56843846..56848265, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene microRNA 497 Neighboring gene uncharacterized LOC134480816 Neighboring gene microRNA 195 Neighboring gene ribonuclease K Neighboring gene arachidonate 12-lipoxygenase, 12S type

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Dou Y, et al. Cell, 2005 Jun 17. PMID 15960975
  2. Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Vermeulen M, et al. Cell, 2010 Sep 17. PMID 20850016
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of MLL1 complex ISO
Inferred from Sequence Orthology
more info
  
part_of NURF complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
chromatin complexes subunit BAP18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127521.3 → NP_001120993.1  chromatin complexes subunit BAP18 isoform 1

    See identical proteins and their annotated locations for NP_001120993.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HG37, B0BNM4
    Conserved Domains (1) summary
    pfam00249
    Location:41 → 77
    Myb_DNA-binding; Myb-like DNA-binding domain

  2. NM_001399718.1 → NP_001386647.1  chromatin complexes subunit BAP18 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    F7F776
    Related
    ENSRNOP00000025491.5, ENSRNOT00000025491.6

  3. NM_001399719.1 → NP_001386648.1  chromatin complexes subunit BAP18 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    Related
    ENSRNOP00000092562.2, ENSRNOT00000113799.2

  4. NM_001399720.1 → NP_001386649.1  chromatin complexes subunit BAP18 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    Conserved Domains (2) summary
    COG1395
    Location:16 → 95
    COG1395; Predicted transcriptional regulator [Transcription]
    pfam00249
    Location:41 → 77
    Myb_DNA-binding; Myb-like DNA-binding domain

  5. NM_001399721.1 → NP_001386650.1  chromatin complexes subunit BAP18 isoform 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I6AVU2

  6. NM_001399722.1 → NP_001386651.1  chromatin complexes subunit BAP18 isoform 6

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

RNA

  1. NR_174343.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    55450648..55453409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268658.1 → XP_063124728.1  chromatin complexes subunit BAP18 isoform X2

  2. XM_063268657.1 → XP_063124727.1  chromatin complexes subunit BAP18 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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