U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sap25 Sin3A-associated protein 25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288559, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Symbol
Sap25provided by RGD
Full Name
Sin3A-associated protein 25provided by RGD
Primary source
RGD:1562406
See related
AllianceGenome:RGD:1562406
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562406
Summary
Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Orthologous to human SAP25 (Sin3A associated protein 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 61.1), Lung (RPKM 38.3) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Sap25 in Genome Data Viewer
Location:
12q12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (24692548..24693683, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19055762..19057425, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22125568..22126671, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene enoyl CoA hydratase domain containing 2, pseudogene 1 Neighboring gene ArfGAP with FG repeats 2 Neighboring gene insulin receptor substrate 3 Neighboring gene leucine rich repeats and calponin homology domain containing 4 Neighboring gene F-box protein 24

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Sin3A-associated protein 25; histone deacetylase complex subunit SAP25
Names
sin3A-binding protein, SAP25

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431969.1 → NP_001418898.1  Sin3A-associated protein 25

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A0A8I6AJ79

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    24692548..24693683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008769160.3 → XP_008767382.1  histone deacetylase complex subunit SAP25

    Conserved Domains (1) summary
    pfam15476
    Location:1 → 239
    SAP25; Histone deacetylase complex subunit SAP25
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials