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Slc37a1 solute carrier family 37 member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 294321, updated on 2-Nov-2024

Summary

Symbol
Slc37a1provided by RGD
Full Name
solute carrier family 37 member 1provided by RGD
Primary source
RGD:1308587
See related
EnsemblRapid:ENSRNOG00000001169 AllianceGenome:RGD:1308587
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable glucose 6-phosphate:phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SLC37A1 (solute carrier family 37 member 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 46.8), Kidney (RPKM 36.5) and 9 other tissues See more
Orthologs
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Genomic context

See Slc37a1 in Genome Data Viewer
Location:
20p12
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (9361733..9435227)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (9360501..9433895)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (10026839..10087691)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene transmembrane serine protease 3 Neighboring gene ubiquitin associated and SH3 domain containing, A Neighboring gene uncharacterized LOC120098980 Neighboring gene radial spoke head component 1 Neighboring gene uncharacterized LOC120098916 Neighboring gene phosphodiesterase 9A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glucose 6-phosphate:phosphate antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glucose 6-phosphate:phosphate antiporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in glucose-6-phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glucose-6-phosphate transport ISO
Inferred from Sequence Orthology
more info
 
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phosphate ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glucose-6-phosphate exchanger SLC37A1
Names
glycerol-3-phosphate transporter
solute carrier family 37 (glucose-6-phosphate transporter), member 1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011944.2NP_001011944.1  glucose-6-phosphate exchanger SLC37A1

    See identical proteins and their annotated locations for NP_001011944.1

    Status: VALIDATED

    Source sequence(s)
    BC081990
    UniProtKB/TrEMBL
    A6JJZ4, Q66H72
    Related
    ENSRNOP00000001544.5, ENSRNOT00000001544.7
    Conserved Domains (1) summary
    cd17344
    Location:21520
    MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    9361733..9435227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039098542.2XP_038954470.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

    UniProtKB/TrEMBL
    A6JJZ4, Q66H72
    Conserved Domains (1) summary
    cd17344
    Location:21520
    MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
  2. XM_017601594.3XP_017457083.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

    UniProtKB/TrEMBL
    A6JJZ4, Q66H72
    Conserved Domains (1) summary
    cd17344
    Location:21520
    MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
  3. XM_017601595.3XP_017457084.1  glucose-6-phosphate exchanger SLC37A1 isoform X1

    UniProtKB/TrEMBL
    A6JJZ4, Q66H72
    Conserved Domains (1) summary
    cd17344
    Location:21520
    MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters
  4. XM_039098543.2XP_038954471.1  glucose-6-phosphate exchanger SLC37A1 isoform X2

    UniProtKB/TrEMBL
    A6JJZ4
    Conserved Domains (1) summary
    cd17344
    Location:21476
    MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters