U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp207 zinc finger protein 207 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303763, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp207provided by RGD
Official Full Name
zinc finger protein 207provided by RGD
Primary source
RGD:1308121
See related
EnsemblRapid:ENSRNOG00000000236 AllianceGenome:RGD:1308121
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable heparin binding activity and microtubule binding activity. Predicted to be involved in several processes, including mitotic nuclear division; mitotic spindle assembly checkpoint signaling; and protein stabilization. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in kinetochore; nucleus; and spindle matrix. Orthologous to human ZNF207 (zinc finger protein 207). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 351.4), Spleen (RPKM 239.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
10q26
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (65883630..65895895)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (65385807..65398086)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (67762970..67784854)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene rhomboid like 3 Neighboring gene similar to human chromosome 17 open reading frame 75 Neighboring gene microRNA 632 Neighboring gene proteasome 26S subunit, non-ATPase 11 Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1 like Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Zep: A novel zinc finger protein containing a large proline-rich domain. Taguchi E, et al. J Biochem, 1998 Dec 1. PMID 9832628
  2. Phase transition of spindle-associated protein regulate spindle apparatus assembly. Jiang H, et al. Cell, 2015 Sep 24. PMID 26388440, Free PMC Article
  3. BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment. Toledo CM, et al. Dev Cell, 2014 Feb 10. PMID 24462187, Free PMC Article
  4. A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting. Jiang H, et al. Dev Cell, 2014 Feb 10. PMID 24462186, Free PMC Article
  5. A method to identify cDNAs based on localization of green fluorescent protein fusion products. Misawa K, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10716735, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC116398

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heparin binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in attachment of spindle microtubules to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in attachment of spindle microtubules to kinetochore ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic sister chromatid segregation ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic spindle assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic spindle assembly checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic spindle assembly checkpoint signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of chromosome segregation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
is_active_in spindle matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle matrix ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
BUB3-interacting and GLEBS motif-containing protein ZNF207

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039020.3 → NP_001034109.1  BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform 1

    See identical proteins and their annotated locations for NP_001034109.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    Q498C9
    Related
    ENSRNOP00000104924.1, ENSRNOT00000156436.1
    Conserved Domains (3) summary
    sd00020
    Location:13 → 34
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam06003
    Location:406 → 441
    SMN; Survival motor neuron protein (SMN)
    cd20908
    Location:10 → 90
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  2. NM_001393767.2 → NP_001380696.1  BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HHB3
    Related
    ENSRNOP00000106957.1, ENSRNOT00000147517.1
    Conserved Domains (3) summary
    sd00020
    Location:13 → 34
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam06003
    Location:437 → 472
    SMN; Survival motor neuron protein (SMN)
    cd20908
    Location:10 → 90
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    65883630..65895895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools