srfa - serum response factor a
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and serum response element binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including adaxial cell; digestive system; musculature system; pericardial region; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in cardiomyopathy and lymphangioleiomyomatosis. Orthologous to human SRF (serum response factor). [provided by Alliance of Genome Resources, Oct 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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