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opn1mw1 opsin 1 (cone pigments), medium-wave-sensitive, 1 [ Danio rerio (zebrafish) ]

Gene ID: 30503, updated on 9-Dec-2024

Summary

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Official Symbol
opn1mw1provided by ZNC
Official Full Name
opsin 1 (cone pigments), medium-wave-sensitive, 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-990604-42
See related
Ensembl:ENSDARG00000097008 AllianceGenome:ZFIN:ZDB-GENE-990604-42
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
RH2-1; rh2.1; zfgr1; grops1
Summary
Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within signal transduction and visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including endocrine system; heart; integument; photoreceptor cell; and visual system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See opn1mw1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (41181882..41183823)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (41184346..41186287)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 22, tandem duplicate 1 Neighboring gene solute carrier family 6 member 22, tandem duplicate 2 Neighboring gene opsin 1 (cone pigments), medium-wave-sensitive, 2 Neighboring gene opsin 1 (cone pigments), medium-wave-sensitive, 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The 1D4 antibody labels outer segments of long double cone but not rod photoreceptors in zebrafish. Yin J, et al. Invest Ophthalmol Vis Sci, 2012 Jul 26. PMID 22743318
  2. Restricted localization of ponli, a novel zebrafish MAGUK-family protein, to the inner segment interface areas between green, red, and blue cones. Zou J, et al. Invest Ophthalmol Vis Sci, 2010 Mar. PMID 19834027, Free PMC Article
  3. Rainbow Enhancers Regulate Restrictive Transcription in Teleost Green, Red, and Blue Cones. Fang W, et al. J Neurosci, 2017 Mar 15. PMID 28193687, Free PMC Article
  4. Predicting peak spectral sensitivities of vertebrate cone visual pigments using atomistic molecular simulations. Patel JS, et al. PLoS Comput Biol, 2018 Jan. PMID 29364888, Free PMC Article
  5. Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia. Krock BL, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360570, Free PMC Article

See all (82) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Six6b and six7 govern expression of the SWS2 and RH2 opsins responsible for middle-wavelength sensitivity.
    Title: Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled photoreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables photoreceptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phototransduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within visual perception IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in photoreceptor outer segment IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in photoreceptor outer segment IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
green-sensitive opsin-1
Names
green cone photoreceptor pigment 1
opsin RH2-1
opsin-1, medium-wave-sensitive 1
rhodopsin-like-2.1 cone opsin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131253.2 → NP_571328.2  green-sensitive opsin-1

    See identical proteins and their annotated locations for NP_571328.2

    Status: PROVISIONAL

    Source sequence(s)
    BC060896
    UniProtKB/Swiss-Prot
    Q8AYM9, Q9W6A5
    UniProtKB/TrEMBL
    A0A0N9NXZ8
    Related
    ENSDARP00000001158.5, ENSDART00000002046.8
    Conserved Domains (3) summary
    pfam00001
    Location:55 → 306
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10413
    Location:2 → 37
    Rhodopsin_N; Amino terminal of the G-protein receptor rhodopsin
    cl21561
    Location:45 → 222
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    41181882..41183823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W6A5.2 GenPept UniProtKB/Swiss-Prot:Q9W6A5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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