foxb1a forkhead box B1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: foxb1aprovided by ZNC
Official Full Name: forkhead box B1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990616-47
See related: Ensembl:ENSDARG00000089042 AllianceGenome:ZFIN:ZDB-GENE-990616-47
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mar; fkd3; cb114; foxb1.2
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within mammillary body development. Predicted to be located in nucleus. Is expressed in several structures, including blastodisc; central nervous system; mesoderm; neural keel; and presumptive structure. Orthologous to human FOXB1 (forkhead box B1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (34154171..34156082, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (33668744..33670655, complement)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fkd3 (e-PCR)
- UniSTS:186958

maripos (e-PCR)
- UniSTS:204696

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in axon target recognition	ISS Inferred from Sequence or Structural Similarity more info
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell migration in diencephalon	ISS Inferred from Sequence or Structural Similarity more info
involved_in floor plate development	ISS Inferred from Sequence or Structural Similarity more info
involved_in hypothalamus cell migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in inferior colliculus development	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mammillary body development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mammillary body development	ISS Inferred from Sequence or Structural Similarity more info
involved_in mammillothalamic axonal tract development	ISS Inferred from Sequence or Structural Similarity more info
involved_in midbrain development	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of neuron apoptotic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in somitogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in telencephalon cell migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in visual learning	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: forkhead box protein B1a

Names: fork head domain protein 3; forkhead box B1.2; forkhead-3; mariposa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.