Hist1h2bq histone cluster 1 H2B family member Q [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Hist1h2bqprovided by RGD
Official Full Name: histone cluster 1 H2B family member Qprovided by RGD
Primary source: RGD:1305011
See related: EnsemblRapid:ENSRNOG00000069578 AllianceGenome:RGD:1305011
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hist1h2bh
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide and innate immune response in mucosa. Predicted to be located in cytosol; extracellular space; and nucleoplasm. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC10 (H2B clustered histone 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 5052.9), Spleen (RPKM 3219.8) and 9 other tissues See more
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Genomic context

Location:: 17p11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (41859955..41869889, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (41432100..41441487, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (43679925..43689311, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Hist1h2bc (e-PCR), detects polymorphism
- UniSTS:259084

RH130284 (e-PCR)
- UniSTS:213571

UniSTS:488584 (e-PCR)
- UniSTS:488584

UniSTS:488587 (e-PCR)
- UniSTS:488587

RH129400 (e-PCR)
- UniSTS:212707

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	ISO Inferred from Sequence Orthology more info
involved_in innate immune response in mucosa	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of nucleosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: histone cluster 1 H2B family member Q

Names: histone 1, H2bh; histone cluster 1, H2bh; histone cluster 1, H2bq

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.