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Zfp518a zinc finger protein 518A [ Rattus norvegicus (Norway rat) ]

Gene ID: 309478, updated on 17-Aug-2024

Summary

Official Symbol
Zfp518aprovided by RGD
Official Full Name
zinc finger protein 518Aprovided by RGD
Primary source
RGD:1305314
See related
EnsemblRapid:ENSRNOG00000036592 AllianceGenome:RGD:1305314
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf518; Znf518a; RGD1305314
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF518A (zinc finger protein 518A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 117.9), Lung (RPKM 81.0) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp518a in Genome Data Viewer
Location:
1q54
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (249668815..249694401)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (239719305..239744978)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (260152881..260178360)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cyclin J Neighboring gene U4 spliceosomal RNA Neighboring gene B-cell linker Neighboring gene uncharacterized LOC120100035 Neighboring gene DNA nucleotidylexotransferase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC124846

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 518A
Names
zinc finger protein 518

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030038.2NP_001025209.1  zinc finger protein 518A

    See identical proteins and their annotated locations for NP_001025209.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    Q499R0
    Related
    ENSRNOP00000092189.1, ENSRNOT00000097947.2
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    249668815..249694401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231397.5XP_006231459.1  zinc finger protein 518A isoform X1

    See identical proteins and their annotated locations for XP_006231459.1

    UniProtKB/Swiss-Prot
    Q499R0
    Related
    ENSRNOP00000106655.1, ENSRNOT00000139822.1
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_039080611.2XP_038936539.1  zinc finger protein 518A isoform X1

    UniProtKB/Swiss-Prot
    Q499R0
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_008760440.4XP_008758662.1  zinc finger protein 518A isoform X1

    See identical proteins and their annotated locations for XP_008758662.1

    UniProtKB/Swiss-Prot
    Q499R0
    Related
    ENSRNOP00000103958.1, ENSRNOT00000126549.1
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_039080620.2XP_038936548.1  zinc finger protein 518A isoform X1

    UniProtKB/Swiss-Prot
    Q499R0
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006231398.5XP_006231460.1  zinc finger protein 518A isoform X1

    See identical proteins and their annotated locations for XP_006231460.1

    UniProtKB/Swiss-Prot
    Q499R0
    Related
    ENSRNOP00000080397.1, ENSRNOT00000111652.2
    Conserved Domains (1) summary
    sd00017
    Location:211231
    ZF_C2H2; C2H2 Zn finger [structural motif]