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arm - armadillo

Enables DNA-binding transcription factor binding activity; kinase binding activity; and transcription coactivator activity. Involved in several processes, including generation of neurons; morphogenesis of an epithelium; and regulation of transcription by RNA polymerase II. Located in several cellular components, including apical plasma membrane; rhabdomere; and zonula adherens. Part of beta-catenin-TCF complex and catenin complex. Is expressed in several structures, including digestive system; embryonic/larval nervous system; gonad; head; and presumptive embryonic/larval system. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including cardiomyopathy (multiple); hepatocellular carcinoma (multiple); palmoplantar keratosis (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to several human genes including CTNNB1 (catenin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Genes similar to arm

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Species Gene Architecture aa