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CG3097 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31503, updated on 10-May-2024

Summary

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Official Symbol
CG3097provided by FlyBase
Primary source
FLYBASE:FBgn0029804
Locus tag
Dmel_CG3097
See related
AllianceGenome:FB:FBgn0029804
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3097
Summary
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including ectoderm; ectoderm anlage; embryonic epidermis; extended germ band embryo; and presumptive embryonic/larval digestive system. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA3 (carboxypeptidase A3); CPA4 (carboxypeptidase A4); and CPA6 (carboxypeptidase A6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG3097 in Genome Data Viewer
Location:
5B8-5C2; 1-14 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5765855..5770780, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5659888..5664813, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45528 Neighboring gene uncharacterized protein Neighboring gene MAP kinase activated protein-kinase-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quantitative Proteomics Identification of Seminal Fluid Proteins in Male Drosophila melanogaster. Sepil I, et al. Mol Cell Proteomics, 2019 Mar 15. PMID 30287546, Free PMC Article
  2. Flexibility in a gene network affecting a simple behavior in Drosophila melanogaster. van Swinderen B, et al. Genetics, 2005 Apr. PMID 15687281, Free PMC Article
  3. Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila. Agrawal N, et al. PLoS Biol, 2021 Nov. PMID 34748544, Free PMC Article
  4. Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses. Findlay GD, et al. PLoS Genet, 2014 Jan. PMID 24453993, Free PMC Article
  5. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metallocarboxypeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metallocarboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3097-PA
NP_572259.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    5765855..5770780 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132031.3 → NP_572259.1  uncharacterized protein Dmel_CG3097 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572259.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W478
    Related
    FBpp0070801
    Conserved Domains (2) summary
    cd03860
    Location:148 → 439
    M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
    pfam02244
    Location:64 → 118
    Propep_M14; Carboxypeptidase activation peptide
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W478 Q9W478

Gene LinkOut

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