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mpc2b mitochondrial pyruvate carrier 2b [ Danio rerio (zebrafish) ]

Gene ID: 321611, updated on 2-Nov-2024

Summary

Official Symbol
mpc2bprovided by ZNC
Official Full Name
mitochondrial pyruvate carrier 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-330
See related
Ensembl:ENSDARG00000024478 AllianceGenome:ZFIN:ZDB-GENE-030131-330
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mpc2; brp44; zgc:56391; zgc:86614; wu:fb22b02; wu:fb22g07
Summary
Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; optic tectum; and pectoral fin. Orthologous to human MPC2 (mitochondrial pyruvate carrier 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See mpc2b in Genome Data Viewer
Location:
chromosome: 9
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (34222027..34227317)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (34412842..34418132)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 161b Neighboring gene ddb1 and cul4 associated factor 6 Neighboring gene neurexophilin and PC-esterase domain family, member 3 Neighboring gene malic enzyme 3, NADP(+)-dependent, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables pyruvate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in mitochondrial pyruvate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mitochondrial pyruvate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mitochondrial pyruvate carrier 2b
Names
brain protein 44
mitochondrial pyruvate carrier 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212592.1NP_997757.1  mitochondrial pyruvate carrier 2b

    See identical proteins and their annotated locations for NP_997757.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049015
    UniProtKB/TrEMBL
    Q7ZUJ3
    Related
    ENSDARP00000031014.7, ENSDART00000028617.8
    Conserved Domains (1) summary
    pfam03650
    Location:24125
    MPC; uncharacterized protein family (UPF0041)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    34222027..34227317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)